Results 131 to 140 of about 138,331 (303)

Serum Proteomic Signatures of RA Risk and Response: Analysis of the APIPPRA Trial

Arthritis &Rheumatology, Accepted Article.
Objective To identify serum protein signatures associated with progression to rheumatoid arthritis (RA) and response to abatacept in at‐risk individuals. Methods A total of 440 serum samples from 118 APIPPRA study participants were selected from baseline to RA onset for 46 RA progressors or to study end for 72 participants who did not develop RA ...
Marianna Jasenecova, Carl Coyle, Alina Mihalovits, Sarah Ryan, Elizabeth Pook, Esperanza Perucha, Gabrielle Harker, Melody Chin, Sam Norton, Andrew P. Cope   +9 more
wiley   +1 more source

Elucidating the bidirectional association between autoimmune diseases and depression: a systematic review and meta-analysis

BMJ Mental Health
Question Collective evidence for the bidirectional association between depression and autoimmune diseases (ADs) is scarce, especially for subgroups of patients with specific ADs.
Yongli Li, Cheng Wang, Changhong Liu, Fang Tang, Shihua Sun, Chengyuan Zhao, Guolin Mi, Guoyong Ding   +7 more
doaj   +1 more source

High frequency of JCV DNA detection in prostate cancer tissues [PDF]

, 2015
BACKGROUND: Prostate cancer (PC) represents the most frequently diagnosed cancer in men. Exposure to infectious agents has been considered to induce prostatic inflammation and cancerous transformation.
Anzivino, Elena, Bellizzi, Anna, Gentile, Vincenzo, Mischitelli, Monica, Pietropaolo, Valeria Antonietta, Rodio, DONATELLA MARIA, Salciccia, Stefano, Sciarra, Alessandro   +7 more
core  

Treatment of a large cohort of childhood chronic non‐infectious uveitis a multicentric large study: adalimumab versus methotrexate as first line therapy

Arthritis &Rheumatology, Accepted Article.
Background Treatment of childhood chronic idiopathic uveitis (cCIU) is predominantly based on studies in Juvenile Idiopathic Arthritis associated uveitis and expert opinion. Our aim was to report the treatment outcomes of our cohort of cCIU. Methods Retrospective multicenter study involving the rheuma/ophthalmology units at Florence and Bristol.
Ilaria Maccora, Catherine Guly, Cinzia de Libero, Giulia Carreras, Athimalaipet V. Ramanan, Gabriele Simonini   +5 more
wiley   +1 more source

Infectious mononucleosis, other infections and prostate-specific antigen concentration as a marker of prostate involvement during infection [PDF]

, 2016
Aksoy, Alanen, Ascherio, Ayatollahi, Banez, Basch, Bergh, Berrington de Gonzalez, Borgermann, Bosch, Carter, Catalona, Chen, Elgamal, Fan, Fedewa, Grinstein, Hasui, Heidenreich, Joshi, Kadayifci, Kadayifci, Kilic, Krystyna, Kuller, Kutok, Lilja, Luzuriaga, Malavaud, Mandel, Moyer, Olsson, Oremek, Rickinson, Rubertone, Sfanos, Silverberg, Sindhwani, Smith, Stamey, Sutcliffe, Sutcliffe, Sutcliffe, Tchetgen, Whitaker, Whittemore, Wolf   +46 more
core   +2 more sources

Pharmacokinetics, pharmacodynamics and safety of vutiglabridin after multiple oral administrations in healthy female and obese subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims Vutiglabridin (HSG4112) is a novel drug under clinical development for antiobesity treatment. This study aimed to evaluate the pharmacokinetics (PKs) and safety of vutiglabridin after multiple oral administrations in healthy Korean female and obese subjects and explore short‐term pharmacodynamic (PD) responses.
Sooyoun Lee, Hyun Chul Kim, Young Ran Yoon, In‐Jin Jang, Sang‐Ku Yoo, Kyung‐Sang Yu   +5 more
wiley   +1 more source

Influence of Patient Gender on In‐Hospital Mortality: A Population‐Based Cross‐Sectional Study

Nursing Open
Aim To analyse the association between gender and in‐hospital mortality odds ratios among patients in the Basque Country. Design Cross‐sectional study.
Nahikari Vizuete‐Aldave, Maider Ugartemendia‐Yerobi, Beatriz Pereda‐Goikoetxea, Nagore Zinkunegi‐Zubizarreta, Josune Zubeldia‐Etxeberria, Udane Elordi‐Guenaga, Haritz Arrieta, Ainitze Labaka   +7 more
doaj   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Clinical research report on Chinese patent medicines and classic traditional Chinese medicine prescriptions (2023)

Digital Chinese Medicine
Objective: Randomized controlled trials (RCTs) of Chinese patent medicines and classic traditional Chinese medicine prescriptions were systematically reviewed from both Chinese and English journals published in 2023.
Xiaolei Wu, Haiyin Hu, Yuetong Wang, Alice Josephine Fauci, Yazi Zhang, Wenting Song, Fengwen Yang, Boli Zhang, Junhua Zhang, Zhaochen Ji   +9 more
doaj   +1 more source