Results 121 to 130 of about 122,730 (293)

Establishment of Interspecies Somatic Cell Nuclear Transfer and Transgene‐Free Inducible Pluripotent Stem Cells for Versatile Conservation of the Germplasm Resource of Wild Boar

Animal Research and One Health, EarlyView.
Conserving genetic material and even increasing genetic diversity is critical. To conduct the conservation of wild boar germplasm resources, we have successfully obtained healthy cloned wild boars for the first time using interspecies somatic cell nuclear transfer and established transgene‐free iPSCs that can be used to conduct iterative rounds of gene
Chen Gao, Xinyi Zhou, Shigang Gu, Jianbo Li, Jing Wang, Yurong Zhang, Wenxuan Zhao, Xinhua Wei, Liting Lu, Quanmin Zhao, Yongye Huang, Dawei Yu   +11 more
wiley   +1 more source

Observed-to-expected ratio (and confidence interval) and total number of excess deaths (ED) for all HWs identified in the MRs for ICD-10 chapters.

ICD-10 chapters: II (Neoplasms), IV (Endocrine, Nutritional and Metabolic Diseases), IX (Diseases of the Circulatory System), V (Mental and Behavioral Disorders), VI (Diseases of the Nervous System), X (Diseases of the Respiratory System), XI (Diseases ...
Leonardo F. Peres (6067001), Ana Russo (13232583), Renata Libonati (6066998), Beatriz N. Garcia (17841238), Helen Gurgel (10399381), Barbara Bresani Salvi (17841244), João L. Geirinhas (17841241), Eliane Lima e Silva (17841247), Djacinto Monteiro dos Santos (17841235), Ricardo M. Trigo (4270495), Julia A. Rodrigues (10802875), Renata Gracie (10471175)   +11 more
core   +1 more source

Spectrum of diseases in a medical ward of a teaching hospital in a developing country

, 2012
Communicable and respiratory tract diseases especially chronic obstructive pulmonary diseases are the main reasons of admission in medical ward of low and middle income countries.
TRS Bedi, R Koju, P Pant, BR Pokharel, R Gurung, S Humagain   +5 more
core   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Ectopic prostatic tissue of the anal canal presenting with rectal bleeding: Report of a case

, 2002
PURPOSE: Ectopic prostatic tissue at various sites within and outside the genitourinary system has been reported previously. A case of ectopic prostatic tissue located in the anal canal causing rectal bleeding is presented.
Özden, Akın, Erdem, Ergün, Yalçın, Nagihan, Çallı, N., Aytekin, Faruk Önder, Sungurtekin, Uğur, Tekin, Koray   +6 more
core   +1 more source

Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie, Joseph F. Merola, Philip J. Mease, Christopher T. Ritchlin, Jose U. Scher, Kimberly Parnell Lafferty, Daphne Chan, Soumya D. Chakravarty, Wayne Langholff, Yanli Wang, Jie Shao, Yevgeniy Krol, Alice B. Gottlieb   +12 more
wiley   +1 more source

Elucidating the bidirectional association between autoimmune diseases and depression: a systematic review and meta-analysis

BMJ Mental Health
Question Collective evidence for the bidirectional association between depression and autoimmune diseases (ADs) is scarce, especially for subgroups of patients with specific ADs.
Yongli Li, Cheng Wang, Changhong Liu, Fang Tang, Shihua Sun, Chengyuan Zhao, Guolin Mi, Guoyong Ding   +7 more
doaj   +1 more source

Genitourinary Diseases Prior Spontaneous Abortion as a Risk Factor for Recurrent Pregnancy Loss

, 2009
The etiology of recurrent spontaneous abortion (RSA) is still unexplained. Many couples do not find the cause of their RSA at all. The purpose of this research was to evaluate the association between recurrent pregnancy loss and previous (cured prior to ...
Matijević, Tanja, Jasminka Pavelić, Vida Čulić, Miše, Kornelija, Kornelija Miše, Čulić, Vida, Kardum, Goran, Goran Kardum, Paško Konjevoda, Konjevoda, Paško, Tanja Matijević, Pavelić, Jasminka   +11 more
core  

Validation of International Classification of Diseases Code–Based Case Definitions of Immune Checkpoint Inhibitor–Associated Inflammatory Arthritis From Administrative Health Data

Arthritis &Rheumatology, EarlyView.
Objective Immune checkpoint inhibitors (ICIs) for cancer can lead to immune‐related adverse events, including ICI‐associated inflammatory arthritis (ICI‐IA). There are no validated International Classification of Diseases (ICD) code–based case definitions for ICI‐IA.
Manar Elsayed, Zoe Hsu, Finlay A. McAlister, William D. Leslie, Lisa M. Lix, Sasha Bernatsky, Suzanne N. Morin, Michelle M. Graham, Aurore Fifi‐Mah, Shahin Jamal, Janet Roberts, Carrie Ye   +11 more
wiley   +1 more source

Combination Therapy in Participants With Active Psoriatic Arthritis Using Subcutaneous Guselkumab and Golimumab: Week 24 Results From a Phase 2a, Multicenter, Randomized, Double‐Blind, Proof‐of‐Concept Study

Arthritis &Rheumatology, EarlyView.
Objective To assess guselkumab + golimumab combination therapy versus guselkumab monotherapy in participants with active psoriatic arthritis (PsA) and inadequate response to tumor necrosis factor inhibitors (TNFi‐IR). Methods Adults with active TNFi‐IR PsA (three or more tender/swollen joints) were randomized (2:1) to subcutaneous guselkumab (100 mg) +
Jose U. Scher, Iain B. McInnes, Enrique R. Soriano, Joseph F. Merola, Paul Bird, Vinod Chandran, Edaire Cheng, Elena Reynoso, Warner Chen, Maoji Li, Lianne S. Gensler, Philip J. Mease, Christopher T. Ritchlin   +12 more
wiley   +1 more source