Results 131 to 140 of about 128,030 (218)

Risk‐reducing gynecologic surgery in hereditary cancer: Evidence, timing, and counseling

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Risk‐reducing gynecologic surgery is an established preventive option for women with selected hereditary cancer predisposition syndromes. In BRCA1 and BRCA2 pathogenic variant carriers, observational studies associate risk‐reducing salpingo‐oophorectomy with lower tubo‐ovarian cancer incidence and mortality.
Agnaldo Lopes da Silva Filho, Giovanni Grandi, Teresa Lamaita Lopes, Angélica Nogueira Rodrigues, Fernando Cotait Maluf, Eduardo Batista Cândido, Rívia Mara Lamaita, Matheus Eduardo Soares Pinhati   +7 more
wiley   +1 more source

Periodontal inflammation may amplify genitourinary vulnerability in perimenopause and postmenopause. [PDF]

Front Cell Infect Microbiol
Zhang Y, Hua J, Li W, Xia B, Yang C, Hou X, Chu W.   +6 more
europepmc   +1 more source

Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Research Progress and Precision Diagnosis‐Therapy Under the Integrated Neuro–Immune–Metabolic–Microbiota Axis Framework

iMetaMed, EarlyView.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang, Jinfei Liu, Qiangsheng Wang, Lei Fan, Ziang Li, Xuexin Yu, Yonghao Chen, Xiaofan Lu, Guiyi Liao, Jialin Meng, Yu Guan   +10 more
wiley   +1 more source

Seasonal and temporal trends in leading causes of hospitalisation among older adults in Hong Kong: a retrospective study across community and institutional care settings. [PDF]

BMJ Open
Qian XX, Chau PH, Lai ETC, Wong GL, Woo J.   +4 more
europepmc   +1 more source

Lactobacillus johnsonii attenuates ovarian aging by remodeling the gut–ovary axis

iMetaOmics, EarlyView.
Aging is accompanied by a reduced abundance of L. johnsonii and ovarian decline. Supplementation with L. johnsonii elevates microbial IPA production via the LdhA enzyme and commensal bacteria. IPA activates the AhR/YAP signaling axis, promoting YAP nuclear translocation and inducing the expression of downstream target genes CYR61 and CTGF. This cascade
Jiamin He, Qiwen Wang, Luyi Chen, Yadong Qi, Dingjiacheng Jia, Jilei Xu, Qingyi Wang, Yao Jiang, Jian Zhou, Yong Sun, Ruochen Yan, Lan Wang, Tongyao Hou, Zheng Kuang, Min Jin, Liangjing Wang, Shujie Chen   +16 more
wiley   +1 more source

Mendelian randomization analyses explore the relationship between inflammatory bowel disease and genitourinary diseases. [PDF]

Medicine (Baltimore)
Cao H, Shi C, Dai X, Yuan B, Yang G, Wang S.   +5 more
europepmc   +1 more source

Artificial intelligence‐driven bioinformatics: From analytical pipelines to model‐centered biological discovery

iMetaOmics, EarlyView.
AI‐driven bioinformatics is best viewed as an emerging model‐centered discovery framework in which learned representations increasingly support prediction, intervention design, and workflow orchestration, while classical pipelines remain essential for validation and reproducibility.
Songming Chen, Wei Zhang, Luohuan Dai, Zujian Xiong, Sicen Lai, Haitao Xu, Jia Gu, Kang Peng, Nian Jiang, Hongwei Liu, Xuejun Li   +10 more
wiley   +1 more source

Plasma proteomic signatures of childhood adversity. [PDF]

Protein Cell
Yu J, Fu D, Wu X, Gao W, Chen H, Jia X, Pu F, Zhao Y, Sun K, Zhang L, Wang W, Huang H, Dearman A, Liu Z.   +13 more
europepmc   +1 more source

Frontiers in transition‐metal single‐atom electrocatalysts: Design tactics, mechanistic regulation, and electrochemical sensing technologies

InfoMat, EarlyView.
This review offers an overview of recent advances in the fundamental properties, synthesis methods, and structural optimization of transition‐metal single‐atom electrocatalysts for electrochemical sensing. It also provides a comprehensive summary of the emerging applications in electrochemical assays based on these materials, along with key challenges ...
Yue Cao, Bo‐Yu Chen, Yiru Sheng, Haoyuan Song, Linan Zhu, Xiaohan Yang, Yuehe Lin, Wenlei Zhu, Yang Zhou   +8 more
wiley   +1 more source

Association of COVID-19 with risks of all-cause and cause-specific mortality post-infection: A UK Biobank cohort study. [PDF]

New Microbes New Infect
Zhang R, Xiang Y, Qiu J, So HC.
europepmc   +1 more source