Results 161 to 170 of about 2,879,932 (270)

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Osteocyte Estrogen Receptor β (Ot‐ERβ) Regulates Bone Turnover and Skeletal Adaptive Response to Mechanical Loading Differently in Male and Female Growing and Adult Mice

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 186-197, January 2023., 2023
ABSTRACT Age‐related bone loss is a failure of balanced bone turnover and diminished skeletal mechanoadaptation. Estrogen receptors, ERα and ERβ, play critical roles in osteoprotective regulation activated by estrogen and mechanical signals. Previous studies mainly focused on ERα and showed that osteocyte‐ERα (Ot‐ERα) regulated trabecular, but not ...
Xiaoyu Xu, Haisheng Yang, Whitney A. Bullock, Maxim A. Gallant, Claes Ohlsson, Teresita M. Bellido, Russell P. Main   +6 more
wiley   +1 more source

HU308 Mitigates Osteoarthritis by Stimulating Sox9‐Related Networks of Carbohydrate Metabolism

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 154-170, January 2023., 2023
ABSTRACT Osteoarthritis (OA) is characterized by progressive, irreversible erosion of articular cartilage accompanied by severe pain and immobility. This study aimed to assess the effect and mechanism of action of HU308, a selective cannabinoid receptor type 2 (CB2) agonist, in preventing OA‐related joint damage. To test the assumption that HU308 could
Idan Carmon, Lital Zecharyahu, Jinan. Elayyan, Sai R. K. Meka, Eli Reich, Leonid Kandel, Andras Bilkei‐Gorzo, Andreas Zimmer, Raphael Mechoulam, Nataly Kravchenko‐Balasha, Mona Dvir‐Ginzberg   +10 more
wiley   +1 more source

The Impact of Microbiota on Musculoskeletal Injuries. [PDF]

Cells
La Placa G, Covino M, Candelli M, Gasbarrini A, Franceschi F, Merra G.   +5 more
europepmc   +1 more source

Irisin in degenerative musculoskeletal diseases: Functions in system and potential in therapy

Pharmacological Research
Degenerative musculoskeletal diseases are a class of diseases related to the gradual structural and functional deterioration of muscles, joints, and bones, including osteoarthritis (OA), osteoporosis (OP), sarcopenia (SP), and intervertebral disc ...
Yu-tong Wang, Sheng-yuan Zheng, Shi-de Jiang, Yan Luo, Yu-xiang Wu, Shinen Naranmandakh, Yu-sheng Li, Shu-guang Liu, Wen-feng Xiao   +8 more
doaj  

Exposure to pseudoephedrine during pregnancy and major congenital malformations: Findings from a large population‐based cohort of pregnancies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of this study was to assess the risk of major congenital malformations following first‐trimester pseudoephedrine (PSE) exposure. Methods A population‐based observational cohort study was conducted on pregnancies of women aged 15–49 years, insured by Clalit Health Services in southern Israel, who gave birth or had elective ...
Saar Dor, Tal Michael, Yael Levi, Gali Pariente, Eitan Lunenfeld, Amalia Levy, Shira Birenstock‐Cohen, Sharon Daniel   +7 more
wiley   +1 more source

Editorial: Role and mechanism of regulated cell death in musculoskeletal development, homeostasis, and diseases. [PDF]

Front Cell Dev Biol
Chen S, Wu X, Chen C.
europepmc   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Reduced exercise capacity is associated with left ventricular systolic dysfunction in long‐term survivors of allogeneic hematopoietic stem‐cell transplantation

Journal of Clinical Ultrasound, Volume 51, Issue 1, Page 5-15, January 2023., 2023
Exercise intolerance is a common complication in long‐term survivors of allogeneic hematopoietic stem‐cell transplantation. In this study, we found reduced oxygen uptake (VO2peak) by cardio‐pulmonary exercise tests to be associated with left ventricular systolic dysfunction by echocardiography.
Richard John Massey, Ole Henrik Myrdal, Phoi Phoi Diep, Marta Maria Burman, Lorentz Brinch, Lars Lysgaard Gullestad, Ellen Ruud, Svend Aakhus, Jan Otto Beitnes   +8 more
wiley   +1 more source

Musculoskeletal Disorders and Diseases: Biomechanical Modeling in Sport, Health, Rehabilitation and Ergonomics. [PDF]

Bioengineering (Basel)
Gorce P.
europepmc   +1 more source