Dupilumab Beyond the Airway: Decreased Morbidity in a Real‐World Analysis
ABSTRACT Background Post hoc analyses of clinical trials have characterized dupilumab's adverse effects, yet the real‐world impact in chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is not well described. This study aims to characterize the risks of lymphoma, cardiovascular events, eosinophilia, joint pain, inflammatory arthritis, and ...
Emma J. Anisman +9 more
wiley +1 more source
Prevalence of musculoskeletal disorders and physiotherapy utilization in primary care - a registry-based study in Sweden. [PDF]
Östlind E, Larsson C, Eek F.
europepmc +1 more source
Novel Approaches for Treating Musculoskeletal Diseases: Molecular Orthopedics and Systems Medicine [PDF]
Kaveh Mashayekhi +3 more
openalex +1 more source
Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques [PDF]
Diamond, Michael S +3 more
core +1 more source
Establishment of a biosafe murine model of skeletal tuberculosis using Mycobacterium smegmatis
This study developed a biosafe, accessible, and versatile murine model of bone TB using Mycobacterium smegmatis, a fast‐growing, nonpathogenic mycobacterial species with high genomic homology to Mycobacterium tuberculosis. Three infection routes—subperiosteal calvarial injection, intratibial injection, and intracardiac (left ventricular) inoculation ...
Yewei Jia +12 more
wiley +1 more source
Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek +7 more
wiley +1 more source
Exploring differences in health-related benefit status in the year before, during and after specialist rehabilitation: a Norwegian case-control study. [PDF]
Skinnes MN +15 more
europepmc +1 more source
3D anatomical atlas of the heads of male and female adult Chamaeleo calyptratus
The veiled chameleon is a model organism in reptile development research. Utilizing contrast‐enhanced microCT and deep learning segmentation models, we have generated the first digital atlases of the skull, nervous system, cranial muscles and hyolingual muscles.
Alice Leavey +3 more
wiley +1 more source

