Results 231 to 240 of about 179,215,740 (302)

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl, Jonathan Grigg, Lubna Abuqayyas, Piotr Kuna, Gillian Hunter, Beata Pawlikowska, Jacob Leander, Michael Levin, Atul Gupta, James Paton, Katharine C. Pike, Jane R. Parnes, Gun Almqvist, Stephanie L. Roseti, on behalf of the study investigators   +14 more
wiley   +1 more source

Changing Patterns of Hospitalisation and Orthopaedic Procedure Profiles in Major Inflammatory Rheumatic Diseases in Germany: a Nationwide Analysis of Hospital Discharge Data. [PDF]

Rheumatol Int
Anees H, Jamous R, Heiss C, El Khassawna T, Biehl C.   +4 more
europepmc   +1 more source

The impact of medication shortages on paediatric care: A retrospective impact analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Medication shortages are a growing global concern, with potentially greater consequences in paediatric patients because of the limited availability of safe, evidence‐based and appropriately formulated medication. This study aimed to evaluate the impact of medication shortages on paediatric patients by assessing the suitability and safety of ...
Maaike Johanna Rutten ‐ van Kranenburg, Laurens Christiaan van Rijn, Elisabeth Johanna Ruijgrok, Sinno Henricus Paulus Simons, Brigitta Carolina Maria Witjes, Jan‐Dietert Christoffer Brugma, Robert Bernard Flint   +6 more
wiley   +1 more source

Intersection of gender and class in the assessment of self-rated health in the Spanish population: a classification tree study. [PDF]

Int J Equity Health
Gumà-Lao J, Barnils NP, La Parra-Casado D.   +2 more
europepmc   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

Ferroptosis in musculoskeletal disorders: Emerging mechanisms and therapeutic opportunities (Review). [PDF]

Int J Mol Med
Gu W, Zhang H, Ye L, Liu F, Xu T, Yu Y, Wang G.   +6 more
europepmc   +1 more source

Low‐Field MRI as a Multiparametric Tool for Large Engineered Tissue Characterization

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Advances in 3D bioprinting have enabled the fabrication of large and complex engineered tissues, but their increasing size demands non‐invasive tools for monitoring structure, maturation, and perfusion. Magnetic Resonance Imaging (MRI) offers unique multiparametric capabilities, yet high‐field systems remain costly and inaccessible for most ...
Yilbert Gimenez, Valernst Martial Gilmus, Elliott Cowles, Lucie Essayan, Vincent Semet, Michel Cabrera, Christophe A. Marquette, Simon A. Lambert, Emma Petiot   +8 more
wiley   +1 more source

The burden of work related musculoskeletal disorders among female beedi workers: a public health perspective. [PDF]

Front Public Health
Amanna S, Bhandary YP, Das R, Shenoy RP, Kotian A.   +4 more
europepmc   +1 more source

Musculoskeletal abnormalities: A clue to systemic diseases

Clinical Imaging
Leonor Garbin Savarese, Larissa Girardi Sangoi, Isadora Balderama Canedo, Mateus de Andrade Hernandes, Valdair Francisco Muglia, Douglas Jorge Racy, Marcello Henrique Nogueira-Barbosa   +6 more
openaire   +1 more source

Diffuse large B-cell lymphoma mimicking musculoskeletal nontuberculous mycobacterial infection: A fatal diagnostic challenge. [PDF]

IDCases
Kim S, Lee SJ.
europepmc   +1 more source