Results 81 to 90 of about 217,243 (262)

Remote Control of Eukaryotic Gene Expression by a Modular Ultrasound‐Responsive RNA Toolkit

Angewandte Chemie, EarlyView.
A modular RNA‐based sonogenetic toolkit enables remote control of gene expression in eukaryotes by releasing small molecule modulators from ultrasound‐responsive carriers. These modulators activate engineered mRNA elements such as riboswitches, leading to tunable protein expression.
Fahimeh Charbgoo, Aman Ishaqat, Junlin Chen, Fabian Wiertz, Adrian Kuzmanović, Matthias Bartneck, Fabian Kiessling, Andreas Herrmann   +7 more
wiley   +2 more sources

Functionalized Biomimetic Nanoparticles Targeting the IL‐10/IL‐10Rα/Glycolytic Axis in Synovial Macrophages Alleviate Cartilage Degeneration in Osteoarthritis

Advanced Science, EarlyView.
The MOF material UIO‐66‐NH2 is functionalized with DBCO groups on its surface, encapsulating NO‐prednisolone and conjugating it with azide‐modified IL‐10. Finally, the complex is extruded with MM to form biomimetic functional nanoparticles. Upon intra‐articular injection, MI@UN, enveloped by the MM, specifically targets synovial macrophages, is ...
Wenwei Li, Yang Liu, Ming Wei, Zhichao Yang, Zhaoyu Li, Zezhong Guo, Liang Yan, Yang Lu, Hao Tang, Bofeng Li, Wei Huang   +10 more
wiley   +1 more source

Medico-social characteristics of patients treated in rehabilitation centres [PDF]

, 2013
Aim: analysis of the medical social characteristics of patients of rehabilitation center. Material and methods. The data that had been got by extracting from medical records of patients of the Center of restorative medicine and rehabilitation «Medical ...
Shapovalenko T.V.
core  

Seguir adelante: A qualitative exploration of Latino farmworkers' work and nonwork resources

American Journal of Community Psychology, EarlyView.
Abstract Latino immigrant workers have been an exploited community within many dangerous workforces, but especially within the agricultural industry. They are a crucial population for the labor and economy of the U.S., yet Latino farmworkers report feeling expendable, discriminated against, and exposed to hazardous working conditions.
Faviola Robles Saenz, Julissa Castellanos Regalado, Larry Martinez, Greg Townley   +3 more
wiley   +1 more source

Occupational Injuries and Illnesses: A Pilot Study of Job-Transfer or Work-Restriction Cases, 2012 [PDF]

, 2014
[Excerpt] The Bureau of Labor Statistics (BLS) conducted a pilot study to learn more about the case circumstances and worker characteristics for occupational injury and illness cases that resulted in days of job transfer or work restriction for workers ...
Bureau of Labor Statistics
core   +2 more sources

Pannexins in the musculoskeletal system: new targets for development and disease progression

Bone Research
AbstractDuring cell differentiation, growth, and development, cells can respond to extracellular stimuli through communication channels. Pannexin (Panx) family and connexin (Cx) family are two important types of channel-forming proteins. Panx family contains three members (Panx1-3) and is expressed widely in bone, cartilage and muscle.
Yan Luo, Shengyuan Zheng, Wenfeng Xiao, Hang Zhang, Yusheng Li   +4 more
openaire   +3 more sources

Applying the NIOSH Worker Well‐Being Framework to Migrant and Seasonal Farmworkers: Insights From the Literature

American Journal of Industrial Medicine, Volume 68, Issue 7, Page 573-587, July 2025.
ABSTRACT Background There is a growing appreciation of the importance of health and well‐being and of the complex set of factors, within and outside the workplace, that interact to affect the well‐being of workers. Migrant and seasonal farmworkers experience particular challenges, and measurement of factors that influence their health and well‐being is
Tessa Bonney, Dana Madigan, Vinay Espinosa‐Ravi, Linda Forst   +3 more
wiley   +1 more source

Phenotypic Characterization of Seven Pediatric Patients Diagnosed With KAT6B‐Related Disorders: Case Series and Review of the Literature

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Genitopatellar syndrome (GPS) and Say‐Barber‐Biesecker‐Young‐Simpson Syndrome (SBBYSS) are clinically distinct neurodevelopmental disorders caused by monoallelic pathogenic variants in KAT6B. In some cases, GPS and SBBYSS features can overlap, determining an intermediate phenotype.
Vittorio Maglione, Antonio Pizzuti, Gioia Mastromoro, Eleonora Cresta, Paola Favata, Maria Cristina Digilio, Rossella Capolino, Maria Lisa Dentici, Lorenzo Sinibaldi, Antonio Novelli, Marco Tartaglia, Gianluca Terrin, Viviana Cardilli   +12 more
wiley   +1 more source

Occupational Musculoskeletal Disorders in Europe: Impact, Risk factors and Preventive Regulations [PDF]

The aim of this article is to characterize musculoskeletal disorders (MSDs) in EU working population according to available Eurostat data, to identify relevant risk factors and to refer existing legislation and standards to prevent MSDs.
José Miquel Cabeças
core   +1 more source

Truncating Variants in RREB1 Cause a Novel RASopathy Syndrome of Congenital Heart Disease, Genitourinary Malformations, and Developmental Delay

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The interstitial 6p microdeletion syndrome is characterized by dysmorphic facies and structural heart, kidney, brain, and musculoskeletal differences. RREB1 haploinsufficiency and consequent abnormal RAS‐MAPK pathway signaling have been proposed as a driver of the disease phenotype; however, apart from a single case report, the phenotype of ...
Alanna Strong, Caoimhe McKenna, Karen Stals, Antonio Vitobello, Mathilde Renaud, Claudine Rieubland, Michel Guipponi, Christophe Philippe, Paul Vrana, Alisa Gaskell, A. Micheil Innes, Alyssa L. Rippert, Rebecca Ahrens‐Nicklas, Elizabeth Bhoj, Kiersten Keller, Bimal P. Chaudhari, Brandon S. Stone   +16 more
wiley   +1 more source