Results 91 to 100 of about 688,083 (239)

Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review. [PDF]

, 2019
As a part of the central nervous system, the retina may reflect both physiologic processes and abnormalities related to diseases of the brain. Indeed, a concerted effort has been put forth to understand how Alzheimer's disease (AD) pathology may manifest
Honma, Patrick, Ngolab, Jennifer, Rissman, Robert A   +2 more
core   +1 more source

Stressed brain, diseased heart : a review on the pathophysiologic mechanisms of neurocardiology [PDF]

, 2013
Cardiovascular diseases are traditionally related to well known risk factors like dyslipidemia, smoking, diabetes and hypertension. More recently, stress, anxiety and depression have been proposed as risk factors for cardiovascular diseases including ...
Cerqueira, João, Palha, Joana Almeida, Pereira, Vitor H., Sousa, Nuno   +3 more
core   +1 more source

Cognitive impairment and mental disorders in patients with focal muscular dystonia

Неврология, нейропсихиатрия, психосоматика, 2019
Non-motor manifestations in focal muscular dystonia (FMD) have been little studied. Objective: to analyze the characteristics of cognitive impairment (CI) and mental disorders (MDs) in FMD. Patients and methods.
V. A. Tolmacheva, D. A. Grishina, D. V. Romanov   +2 more
doaj   +1 more source

NMR metabolomics of cerebrospinal fluid differentiates inflammatory diseases of the central nervous system [PDF]

, 2018
BACKGROUND: Myriad infectious and noninfectious causes of encephalomyelitis (EM) have similar clinical manifestations, presenting serious challenges to diagnosis and treatment.
Amzuta, Ioana G., Brunner, Andrew M., David, Dan, Encarnacion, Rafael, Fatteh, Naaz, Fernandez, Josefina, Foley, John F., French, Caitlin D., Hu, William T., Javaid, Waleed, Mishchuk, Darya O., Neilan, Anne M., Ondrush, Joanne M., Paez, Andres, Pan, Amy, Robbins, Gregory K., Slupsky, Carolyn M., Wheat, L. Joseph, Willoughby, Rodney E., Wong, Susan J.   +19 more
core   +3 more sources

Targeted up-regulation of Drp1 in dorsal horn attenuates neuropathic pain hypersensitivity by increasing mitochondrial fission

Redox Biology, 2022
Mitochondria play an essential role in pathophysiology of both inflammatory and neuropathic pain (NP), but the mechanisms are not yet clear. Dynamin-related protein 1 (Drp1) is broadly expressed in the central nervous system and plays a role in the ...
Kun-Long Zhang, Shu-Jiao Li, Xue-Yin Pu, Fei-Fei Wu, Hui Liu, Rui-Qing Wang, Bo-Zhi Liu, Ze Li, Kai-Feng Li, Nian-Song Qian, Yan-Ling Yang, Hua Yuan, Ya-Yun Wang   +12 more
doaj  

The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1 [PDF]

, 2009
Defective responses to DNA single strand breaks underlie various neurodegenerative diseases. However, the exact role of this repair pathway during the development and maintenance of the nervous system is unclear. Using murine neural-specific inactivation
A Kulkarni, A Lee, A Weyer, AM Kenney, C Englund, C Sotelo, D Goldowitz, D Watanabe, E Aronica, E Soutoglou, EA Lumpkin, EP Rogakou, ER Shull, G Weisheit, H Takashima, H Yamanaka, Helen R Russell, I Ahel, JC Eccles, JI Morgan, JM Huard, JO McNamara, K Leto, KE Orii, Keith W Caldecott, KW Caldecott, KW Caldecott, KW Caldecott, L Zhang, MB Kastan, MC Moreira, MD Tallquist, ME Hatten, NH Barmack, OA Sedelnikova, OW Howell, P Rakic, Peter J McKinnon, PJ McKinnon, PJ McKinnon, PO Frappart, PO Frappart, RS Tebbs, RV Sillitoe, S Katyal, Sachin Katyal, SB Glickstein, SC Baraban, SF El-Khamisy, Sherif F El-Khamisy, SM Maricich, U Rass, VY Wang, Y Lee, Y Lee, Yang Li, Youngsoo Lee   +56 more
core   +1 more source

Gut dysbiosis breaks immunological tolerance toward the central nervous system during young adulthood

Proceedings of the National Academy of Sciences of the United States of America, 2017
Significance Multiple sclerosis (MS) is classified as an autoimmune disease of the central nervous system (CNS). Alterations of gut microbiota (gut dysbiosis) are frequently observed in MS patients.
S. Yadav, S. Boppana, N. Ito, John E. Mindur, Martin Mathay, Ankoor Patel, S. Dhib-Jalbut, Kouichi Ito   +7 more
semanticscholar   +1 more source

Purinergic signalling: past, present and future [PDF]

, 2009
The discovery of non-adrenergic, non-cholinergic neurotransmission in the gut and bladder in the early 1960's is described as well as the identification of adenosine 5'-triphosphate (ATP) as a transmitter in these nerves in the early 1970's.
Burnstock, G
core   +1 more source

Long-term survival for a cohort of adults with cerebral palsy [PDF]

, 2006
The aim of this study was to investigate long-term survival and examine causes of death in adult patients with cerebral palsy (CP). A 1940–1950 birth cohort based on paediatric case referral allows for long-term survival follow-up.
Blair, Cox, Evans, Evans, Hutton, Hutton, Hutton, Jane L Hutton, Karla Hemming, Maudsley, Peter O D Pharoah, Strauss, Strauss, Strauss, Strauss, Surveillance of Cerebral Palsy in Europe., Woods, Woods, Woods   +18 more
core   +1 more source

Effects of feline immunodeficiency virus on astrocyte glutamate uptake: implications for lentivirus-induced central nervous system diseases.

Proceedings of the National Academy of Sciences of the United States of America, 1998
Feline immunodeficiency virus (FIV) is a lentivirus of domestic cats that causes a spectrum of diseases remarkably similar to AIDS in HIV-infected humans. As part of this spectrum, both HIV-1 and FIV induce neurologic disorders.
N. Yu, J. Billaud, T. Phillips
semanticscholar   +1 more source