Results 101 to 110 of about 1,542,715 (367)
ABSTRACT Objectives Repetitive transcranial magnetic stimulation (rTMS) is a non‐invasive brain stimulation strategy with a demonstrated potential to reinforce the residual pathways after a spinal cord injury (SCI). A preclinically tested high‐frequency (15 Hz) rTMS (15 Hz rTMS) protocol was shown to induce corticospinal tract axon regeneration growth ...
Nabila Brihmat+8 more
wiley +1 more source
Facet joint osteoarthritis as a cause of chronic low back pain
Chronic nonspecific low back pain (LBP) is the most common cause of disability and a lower quality of life in modern society.Objective: to discuss the feasibility of identifying the causes of chronic nonspecific LBP and in the case of detection of damage
D. O. Rozhkov+3 more
doaj +1 more source
Research progress of spinophilin in nervous system diseases [PDF]
Spinophilin (SPN) was first isolated from the dendritic spines of neurons as a binding protein of protein phosphatase PP1, it is also known as PPP1R9B.
XING Jing-song, KE Tian-tian, ZHANG Lin, LIANG Dong, ZHANG Tong, GAO Shang-feng
doaj
ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells [PDF]
The RhoA and RhoC GTPases act via the ROCK1 and ROCK2 kinases to promote actomyosin contraction, resulting in directly induced changes in cytoskeleton structures and altered gene transcription via several possible indirect routes.
Clark, William+3 more
core +1 more source
ABSTRACT Objective To investigate the overall use of prescription medications among individuals with multiple sclerosis compared to the general population, with a focus on treatments beyond disease‐modifying therapies. Methods We conducted a nationwide, registry‐based study in Denmark.
Josefine Windfeld‐Mathiasen+4 more
wiley +1 more source
Background & Aims: The presence of myenteric plexitis in the proximal resection margins is a predictive factor of early postoperative recurrence in Crohn’s disease.
Julie Pabois+13 more
doaj +1 more source
Serum amyloid A primes microglia for ATP-dependent interleukin-1\u3b2 release [PDF]
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A (SAA).
A Basu+82 more
core +2 more sources
The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh+22 more
wiley +1 more source
Significance Multiple sclerosis (MS) is classified as an autoimmune disease of the central nervous system (CNS). Alterations of gut microbiota (gut dysbiosis) are frequently observed in MS patients.
S. Yadav+7 more
semanticscholar +1 more source
Glioblastoma (GBM) is the most aggressive primary brain tumor with a grim prognosis and low survival rates. This unfavorable therapeutic outcome is partially because of the inadequate immune infiltration and an immunosuppressive microenvironment, which ...
Lansheng Wang+11 more
doaj +1 more source