Results 101 to 110 of about 1,542,715 (367)

Translating a Preclinically Tested 15 Hz rTMS Protocol to Humans With Chronic Spinal Cord Injury: A Safety and Feasibility Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Repetitive transcranial magnetic stimulation (rTMS) is a non‐invasive brain stimulation strategy with a demonstrated potential to reinforce the residual pathways after a spinal cord injury (SCI). A preclinically tested high‐frequency (15 Hz) rTMS (15 Hz rTMS) protocol was shown to induce corticospinal tract axon regeneration growth ...
Nabila Brihmat   +8 more
wiley   +1 more source

Facet joint osteoarthritis as a cause of chronic low back pain

open access: yesНеврология, нейропсихиатрия, психосоматика, 2019
Chronic nonspecific low back pain (LBP) is the most common cause of disability and a lower quality of life in modern society.Objective: to discuss the feasibility of identifying the causes of chronic nonspecific LBP and in the case of detection of damage
D. O. Rozhkov   +3 more
doaj   +1 more source

Research progress of spinophilin in nervous system diseases [PDF]

open access: yesJichu yixue yu linchuang, 2021
Spinophilin (SPN) was first isolated from the dendritic spines of neurons as a binding protein of protein phosphatase PP1, it is also known as PPP1R9B.
XING Jing-song, KE Tian-tian, ZHANG Lin, LIANG Dong, ZHANG Tong, GAO Shang-feng
doaj  

ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells [PDF]

open access: yes, 2016
The RhoA and RhoC GTPases act via the ROCK1 and ROCK2 kinases to promote actomyosin contraction, resulting in directly induced changes in cytoskeleton structures and altered gene transcription via several possible indirect routes.
Clark, William   +3 more
core   +1 more source

Medication Use in Multiple Sclerosis: A Population‐Based Comparison With the General Danish Population

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the overall use of prescription medications among individuals with multiple sclerosis compared to the general population, with a focus on treatments beyond disease‐modifying therapies. Methods We conducted a nationwide, registry‐based study in Denmark.
Josefine Windfeld‐Mathiasen   +4 more
wiley   +1 more source

Role of ICAM-1 in the Adhesion of T Cells to Enteric Glia: Perspectives in the Formation of Plexitis in Crohn’s DiseaseSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology
Background & Aims: The presence of myenteric plexitis in the proximal resection margins is a predictive factor of early postoperative recurrence in Crohn’s disease.
Julie Pabois   +13 more
doaj   +1 more source

Serum amyloid A primes microglia for ATP-dependent interleukin-1\u3b2 release [PDF]

open access: yes, 2018
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A (SAA).
A Basu   +82 more
core   +2 more sources

The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh   +22 more
wiley   +1 more source

Gut dysbiosis breaks immunological tolerance toward the central nervous system during young adulthood

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
Significance Multiple sclerosis (MS) is classified as an autoimmune disease of the central nervous system (CNS). Alterations of gut microbiota (gut dysbiosis) are frequently observed in MS patients.
S. Yadav   +7 more
semanticscholar   +1 more source

Cascade reaction–driven biomimetic scintillant/metal–organic frameworks for X-ray triggered combinational therapy against glioma

open access: yesMaterials Today Bio
Glioblastoma (GBM) is the most aggressive primary brain tumor with a grim prognosis and low survival rates. This unfavorable therapeutic outcome is partially because of the inadequate immune infiltration and an immunosuppressive microenvironment, which ...
Lansheng Wang   +11 more
doaj   +1 more source

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