Results 111 to 120 of about 1,195,331 (367)

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Acute Respiratory Infections (ARIs) Among Outpatient Healthcare Personnel (HCP)

Open Forum Infectious Diseases, 2016
1756. Acute Respiratory Infections (ARIs) Among Outpatient Healthcare Personnel (HCP) Amanda Krosche, BS; Mary Bessesen, MD; Derek Cummings, PhD; Charlotte Gaydos, DrPH, FIDSA; Cynthia Gibert, MD, MSc, FIDSA; Geoffrey Gorse, MD, FIDSA; Jenna Los, MLA ...
Amanda Krosche, M. Bessesen, D. Cummings, C. Gaydos, C. Gibert, G. Gorse, Jenna G. Los, A. Nyquist, C. Price, L. Radonovich, N. Reich, M. Rodriguez‐Barradas, M. Simberkoff, T. Perl, The ResPECT Study Team   +14 more
semanticscholar   +1 more source

Health risks associated with the use of automatic milk feeders in calves [PDF]

, 2016
The objective of the present article was to summarize available evidence of the economic benefits and health risks associated with the use of automatic milk feeders (AMFs) in calves.
Boyen, Filip, Deprez, Piet, Gille, Linde, Janssens, Karlijn, Pardon, Bart, Valgaeren, Bonnie, Van Driessche, Laura   +6 more
core  

End-to-End Knowledge-Routed Relational Dialogue System for Automatic Diagnosis

, 2019
Beyond current conversational chatbots or task-oriented dialogue systems that have attracted increasing attention, we move forward to develop a dialogue system for automatic medical diagnosis that converses with patients to collect additional symptoms ...
Gong, Ke, Liang, Xiaodan, Lin, Liang, Tang, Jianheng, Xu, Lin, Zhou, Qixian   +5 more
core   +1 more source

In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock, Jihyun Park, Dae‐Gyu Jang, Bangyao Zhao, Samuel J. Teener, Ian F. Webber‐Davis, Lili Zhao, Eva L. Feldman, Stephen A. Goutman   +8 more
wiley   +1 more source

Research Progress on Chinese Medicine Regulation of Mitochondrial Damage for Intervention in Respiratory System Diseases

Chinese Medicine and Natural Products
Mitochondria are important organelles in cells for energy production, and mitochondrial damage caused by various reasons is an important factor promoting disease progression.
Haibo Li, Jingfan Yang, Yanqin Qin, Tiantian Liu   +3 more
doaj   +1 more source

Monitoring of Respiratory Infections in the Intensive Area of Respiratory System Disease

Advances in Microbiology, 2014
Respiratory infections are the most frequent nosocomial infections after those urinaries and surgicals. We analysed respiratory infection incidences in patients treated with different kinds of respiratory assistance (non-invasive ventilation and invasive mechanical ventilation trough tracheostomy), studying 640 patients recovering in the intensive
Filippo Ricciardiello, Maria Cardone, FIORENTINO, GIUSEPPE, MESOLELLA, MASSIMO, Flavia Oliva, Annalisa Pianese, Carlo Antonio Leone   +6 more
openaire   +4 more sources

The effect of short-term changes in air pollution on respiratory and cardiovascular morbidity in Nicosia, Cyprus. [PDF]

, 2007
Presented at the 6th International Conference on Urban Air Quality, Limassol, March, 2007. Short-paper was submitted for peer-review and appears in proceedings of the conference.This study investigates the effect of daily changes in levels of PM10 on the
Demokritou, Philip, Dockery, Douglas W., Kleanthous, Savvas, Kolokotroni, Ourania, Koutrakis, Petros, Middleton, Nicos, Schwartz, Joel D., Yiallouros, Panayiotis K.   +7 more
core   +1 more source

Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó, Igor Stevanovski, Germán Morís, Roger Collet‐Vidiella, Alba Segarra‐Casas, Lidia González‐Quereda, Benjamín Rodríguez‐Santiago, Pia Gallano, Rodrigo Alvarez, Ana Vesperinas, Rosa Blanco, Beatriz San‐Millán, Carmen Navarro, Isabel Illa, Gianina Ravenscroft, Ira W. Deveson, Eduard Gallardo, Montse Olivé   +17 more
wiley   +1 more source

Hospitalisation patterns for respiratory diseases in Australia: an ecological study

BMJ Open
Objectives The objective of this study is to examine the hospitalisation profile for respiratory diseases in Australia between 1998 and 2019.Design An ecological study.Setting A population study that involved all private and public hospitalisations for ...
Abdallah Y Naser, Saeed Mardy Alghamdi, Jaber S Alqahtani, Yousef S Aldabayan, Ahmed Alrajeh, Rayan A Siraj, Abdulelah Mastour Aldhahir, Yousif Mohammed Elmosaad, Mahmudul Hassan Al Imam, Ahmed Al Haykan   +9 more
doaj   +1 more source