Results 61 to 70 of about 1,283,464 (326)

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

National mortality burden due to communicable, non-communicable, and other diseases in Ethiopia, 1990–2015: findings from the Global Burden of Disease Study 2015 [PDF]

, 2017
Background: Ethiopia lacks a complete vital registration system that would assist in measuring disease burden and risk factors. We used the Global Burden of Diseases, Injuries, and Risk factors 2015 (GBD 2015) estimates to describe the mortality burden ...
A Misganaw, A Misganaw, Amare Deribew, AR Omran, Awoke Misganaw, Azmeraw T. Amare, B Weldearegawi, Biruck Desalegn Yirsaw, Central Statistical Agency (CSA) [Ethiopia] and ICF, CJL Murray, D Chandramohan, D Hailemariam, D Shamebo, D Shamebo, F Tesfaye, F Tesfaye, Federal Ministry of Health, Ethiopia, GA Biks, GBD 2013 Mortality and Causes of Death Collaborators, Gizachew Assefa Tessema, H Wang, Jed Blore, K Lulu, Kebede Deribe, Kristopher J. Krohn, L Chaker, M Naghavi, Mesoud Mohammed, MH Forouzanfar, Mohsen Naghavi, Molla Gedefaw, Muluken Dessalegn, NJ Kassebaum, P Byass, S Accorsi, S Kuruvilla, Semaw Ferede Abera, Solomon Abrha Damtew, T Araya, Tilahun N. Haregu, Tolesa Bekele, Tom Achoki, W Deressa, Yibeltal Assefa, Yihunie Lakew, Yohannes Adama Melaku   +45 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Advances in Diagnostics and Management of Respiratory System Diseases

Diagnostics, 2023
Recently, significant innovations in the diagnosis and management of respiratory diseases have been developed [...]
Paola Confalonieri, Francesco Salton, Marco Confalonieri, Riccardo Pozzan, Barbara Ruaro   +4 more
openaire   +3 more sources

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Denz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Understanding Viral Transmission Behavior via Protein Intrinsic Disorder Prediction: Coronaviruses [PDF]

, 2012
Besides being a common threat to farm animals and poultry, coronavirus (CoV) was responsible for the human severe acute respiratory syndrome (SARS) epidemic in 2002-4. However, many aspects of CoV behavior, including modes of its transmission, are yet to
Dunker, A. Keith, Goh, Gerard Kian-Meng, Uversky, Vladmir N.   +2 more
core   +3 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Comparative analysis of immunity system indicators among patients with infectious diseases of the respiratory system

Aktualʹnaâ Infektologiâ, 2019
The article provides data on the relevance of acute respiratory diseases and pneumonia among militaries. The purpose of this work was to study the status of the immune system in military personnel during anti-terrorist operation, patients with acute ...
O.A. Raksha-Slіusareva, V.I. Trykhlib, O.A. Slіusarev, I.A. Tarasova, V.V. Alekseenko   +4 more
doaj   +1 more source

Elderly Nutrition Problems. [PDF]

, 2014
In old age people suffer from internal organs diseases very often. More than 90% of the elderly have these diseases. As much as one third of all older people complain of cardiovascular, respiratory and digestive diseases, diseases of the ...
Кравченко, В. С.
core