Results 71 to 80 of about 1,342,089 (291)

The respiratory neuromuscular system in Pompe disease [PDF]

open access: yesRespiratory Physiology & Neurobiology, 2013
Pompe disease is due to mutations in the gene encoding the lysosomal enzyme acid α-glucosidase (GAA). Absence of functional GAA typically results in cardiorespiratory failure in the first year; reduced GAA activity is associated with progressive respiratory failure later in life.
David D, Fuller   +6 more
openaire   +3 more sources

Concentration of cytokines in blood serum of children suffering from acute obstructive bronchitis and thymomegalia. [PDF]

open access: yes, 2014
Recently children suffering from acute obstructive bronchitis (AOB) need increased attention of Ukrainian doctors due to the fact that almost 30% of all patients having respiratory diseases suffer from this pathology.
Plakhuta, Valentyna Anatoliivna   +2 more
core  

Effects of chlorhexidine gluconate oral care on hospital mortality : a hospital-wide, observational cohort study [PDF]

open access: yes, 2018
Chlorhexidine oral care is widely used in critically and non-critically ill hospitalized patients to maintain oral health. We investigated the effect of chlorhexidine oral care on mortality in a general hospitalized population.
Blot, Stijn   +4 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Impact of electronic cigarette usage on the onset of respiratory symptoms and COPD among Chinese adults

open access: yesScientific Reports
The prevalence of dual usage and the relatively low cessation rate among e-cigarette (EC) users suggest that ECs have not demonstrated significant effectiveness as a smoking cessation tool.
Beibei Song   +4 more
doaj   +1 more source

Potentially Diagnostic Electron Paramagnetic Resonance Spectra Elucidate the Underlying Mechanism of Mitochondrial Dysfunction in the Deoxyguanosine Kinase Deficient Rat Model of a Genetic Mitochondrial DNA Depletion Syndrome [PDF]

open access: yes, 2016
A novel rat model for a well-characterized human mitochondrial disease, mitochondrial DNA depletion syndrome with associated deoxyguanosine kinase (DGUOK) deficiency, is described.
Bennett, Brian   +8 more
core   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Housing, management and health in Swedish dairy calves [PDF]

open access: yes, 2004
This thesis discusses the results of an observational study conducted in dairy herds in the south-western Sweden and a questionnaire survey of dairy herds done throughout Sweden.
Lundborg, Karin
core  

Syndromic and Point-of-Care Molecular Testing [PDF]

open access: yes, 2018
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Abbott, April N., Relich, Ryan F.
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

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