Results 71 to 80 of about 209,845 (305)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
, 1991 A quick release toggle clamp that utilizes a spring that requires a deliberate positive action for disengagement is presented. The clamp has a sliding bolt that provides a latching mechanism.
Calco, Frank S.
core +1 more source
Perceptual Control Theory for Engagement and Disengagement of Users in Public Spaces [PDF]
, 2017 This paper presents Perceptual Control Theory-a model that explains behaviour as an attempt to keep sensory inputs in a desired range and demonstrates that it can be used to develop an approach designed to make robots capable of human interaction.
Deshmukh, Amol +2 more
core +1 more source
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source
The seed of goal-related doubts : a longitudinal investigation of the roles of failure and expectation of success among police trainee applicants [PDF]
, 2019 Various theories on personal goal striving rely on the assumption that failure raises doubts about the goal. Yet, empirical evidence for an association between objective failure experiences and doubts about personal long-term goals is still missing. In a
Bettschart, Martin +3 more
core +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Diligentia: Journal of Theology and Christian EducationThe idea of human belief in curses poses a problem for the curse part in Psalms. Problem of misunderstanding the curses part of Psalm 83:1-19 arises among believers.
Samuel Ntsanwisi
doaj +1 more source
A VUCA ACTION FRAMEWORK FOR A VUCA ENVIRONMENT. LEADERSHIP CHALLENGES AND SOLUTIONS [PDF]
Journal of Defense Resources Management, 2016 The 1990 coinage describing the surrounding environment as volatile, uncertain, complex and agile (VUCA) is becoming a cliché in the absence of a more profound analysis.
Aura Codreanu
doaj
Arthritis Care &Research, EarlyView.Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts (Approaches to Positive, Patient‐Centered Experiences of Aging with Lupus [APPEAL] and California Lupus Epidemiology Study
Mrinalini Dey +8 more
wiley +1 more source
When Does Disengagement Correlate with Performance in Spoken Dialog Computer Tutoring? [PDF]
, 2012 In this paper we investigate how student disengagement relates to two performance metrics in a spoken dialog computer tutoring corpus, both when disengagement is measured through manual annotation by a trained human judge, and also when disengagement is ...
Forbes-Riley, Kate, Litman, Diane J
core +1 more source