Results 101 to 110 of about 174,103 (341)

Effects of Overlapping Generations on Linkage Disequilibrium Estimates of Effective Population Size

open access: yesGenetics, 2014
Use of single-sample genetic methods to estimate effective population size has skyrocketed in recent years. Although the underlying models assume discrete generations, they are widely applied to age-structured species.
R. Waples, T. Antão, G. Luikart
semanticscholar   +1 more source

Il persistente squilibrio della bilancia dei pagamenti tedesca.

open access: yesMoneta e Credito, 2014
The work examines Germany’s balance-of-payments surplus. The author first briefly considers the United States balance of payments. The German balance of payments is then analysed according to structural aspects, absorption, the level of domestic ...
C.P. KINDLEBERGER
doaj   +1 more source

Genetic causal association between heart failure, frailty and poisoning by narcotics and psychodysleptics: A two‐sample Mendelian randomization

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Observational studies have suggested associations between heart failure (HF), frailty and poisoning by narcotics and psychodysleptics (PNP). However, establishing causal relationships has been challenging. This study used a two‐sample Mendelian randomization (MR) approach to investigate the genetically proxied causality between HF ...
Bing Wang   +3 more
wiley   +1 more source

Credibility of genetic predictors for antiepileptic drug resistance: A systematic Bayesian reappraisal of published meta‐analyses

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
We systematically reappraised meta‐analyses of pharmacogenetic studies to evaluate the credibility of association between gene polymorphisms and resistance to anti‐epileptic drugs (AEDs). A systematic search was performed in PubMed, Web of Knowledge, Cochrane Library and OpenGrey up to April 2025.
Martina Giacon   +2 more
wiley   +1 more source

Balance-sheet of the first year of the E.R.P. in Italy

open access: yesPSL Quarterly Review, 2014
The article sums up the fundamental data relating to the implementation of the ERP in Italy, pointing out the differences with developments in other countries, the characteristic features and the significance of the help received, the formation and ...
G. COSMO
doaj   +1 more source

Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits

open access: yesGenome Research, 2014
DNA variants (SNPs) that predispose to common traits often localize within noncoding regulatory elements such as enhancers. Moreover, loci identified by genome-wide association studies (GWAS) often contain multiple SNPs in linkage disequilibrium (LD ...
Olivia Corradin   +8 more
semanticscholar   +1 more source

Interrogating the Economic, Environmental, and Social Impact of Artificial Intelligence and Big Data in Sustainable Entrepreneurship

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Artificial intelligence and big data are increasingly being integrated into sustainable entrepreneurship practices. Yet, conventional literature often neglects to critically examine their economic, environmental, and social implications. We conducted a systematic literature review to understand when, how, and for whom artificial intelligence ...
Nathanael Ojong
wiley   +1 more source

Germany’s persistent balance-of-payments disequilibrium revisited

open access: yesPSL Quarterly Review, 2014
The work examines Germany’s balance-of-payments surplus. The author first briefly considers the United States balance of payments. The German balance of payments is then analysed according to structural aspects, absorption, the level of domestic ...
C.P. KINDLEBERGER
doaj   +1 more source

Linking environmental filtering and disequilibrium to biogeography with a community climate framework.

open access: yesEcology, 2015
We present a framework to measure the strength of environmental filtering and disequilibrium of the species composition of a local community across time, relative to past, current, and future climates. We demonstrate the framework by measuring the impact
B. Blonder   +12 more
semanticscholar   +1 more source

Lipid metabolism reprograming by SREBP1‐PCSK9 targeting sensitizes pancreatic cancer to immunochemotherapy

open access: yesCancer Communications, EarlyView.
Abstract Background Pancreatic cancer's aberrant lipid metabolism fuels cell growth, invasion, and metastasis, yet its impact on immune surveillance and immunotherapy is unclear. This study investigated how sterol regulatory element‐binding transcription factor 1 (SREBP1)‐driven lipid metabolism affects the tumor microenvironment (TME) in pancreatic ...
Mengyi Lao   +12 more
wiley   +1 more source

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