Results 161 to 170 of about 308,435 (331)

A Genome‐Wide Association Study of Colorectal Cancer Mortality Outcomes Among Individuals of African and Admixture Ancestry

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT African Americans have the highest colorectal cancer (CRC) mortality rates in the United States. We performed the first genome‐wide association study (GWAS) of overall and CRC‐specific mortality among African Americans with incident CRC to identify genetic contributors to CRC outcomes.
Thomas Lawler   +7 more
wiley   +1 more source

Disequilibrium [PDF]

open access: yesJournal of Medical Humanities, 2019
openaire   +1 more source

Vestibular Dysfunction in Parkinson's Disease: A Systematic Review of Signs and Symptoms

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Despite the growing interest in the link between Parkinson's disease (PD) neuropathology and vestibular system, there is still a lack of consensus about the presence of vestibular dysfunctions in PD. Objective This review aims to identify vestibular signs and symptoms reported in PD patients and to summarize and critically appraise ...
Francisco Rosado‐Martins   +5 more
wiley   +1 more source

Whole-genome Linkage Disequilibrium Maps for European and African Populations

open access: gold, 2019
M. Reza Jabalameli   +5 more
openalex   +1 more source

MendelR: A One‐Stop R Toolkit for Mendelian Randomization Analysis

open access: yesMed Research, EarlyView.
ABSTRACT MendelR is a fully automated R package specifically developed for Mendelian randomization (MR) studies, designed to address the technical challenges of causal inference in biomedical research. As a powerful causal inference method, Mendelian randomization can effectively reduce confounding bias in observational studies.
Xiaohong Ke   +4 more
wiley   +1 more source

LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang   +12 more
wiley   +1 more source

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