Results 251 to 260 of about 174,103 (341)

Maximising the Potential of Temporal Ne$$ {\boldsymbol{N}}_{\mathbf{e}} $$ Estimation in Long‐Term Population Monitoring Programmes

Molecular Ecology Resources, EarlyView.
Tin‐Yu J. Hui
wiley   +1 more source

Associations of plasma sex‐related hormone and protein levels and alcohol dependence

Addiction, EarlyView.
Abstract Background and Aims Sex‐related hormones and proteins may underlie sex differences in alcohol use disorder characteristics and consequences. Previous reports suggest steroid sex hormones may influence alcohol consumption behaviors while proteins that regulate their circulation levels are rarely investigated.
Ada Man‐Choi Ho, Jennifer R. Geske, Vanessa K. Pazdernik, T. Cameron Waller, Anthony Batzler, Stacey J. Winham, Victor M. Karpyak   +6 more
wiley   +1 more source

Analysis of the <i>DYNC1H1</i> Gene Polymorphic Variants' Association with ASD Occurrence and Clinical Phenotype of Affected Children. [PDF]

Genes (Basel)
Balcerzyk-Matić A, Iwanicki T, Jarosz A, Nowak T, Emich-Widera E, Kazek B, Kapinos-Gorczyca A, Kapinos M, Iwanicka J, Gawron K, Likus W, Niemiec P.   +11 more
europepmc   +1 more source

Methods for multiancestry genome‐wide association study meta‐analysis

Annals of Human Genetics, EarlyView.
Abstract Genome‐wide association studies (GWAS) have significantly enhanced our understanding of the genetic basis of complex diseases. Despite the technological advancements, gaps in our understanding remain, partly due to small effect sizes and inadequate coverage of genetic variation.
Chuan Fu Yap, Andrew P. Morris
wiley   +1 more source

Revealing Putative Causal Genes by Establishing the Causality Between Different Lymphomas and Immune Cells. [PDF]

J Cell Mol Med
Lian J, Zhang X, Chen W, Lin Z, Lu M, Liang R.   +5 more
europepmc   +1 more source

The molecular basis of lactase persistence: Linking genetics and epigenetics

Annals of Human Genetics, EarlyView.
Abstract Lactase persistence (LP) — the genetic trait that determines the continued expression of the enzyme lactase into adulthood — has undergone recent, rapid positive selection since the advent of animal domestication and dairying in some human populations.
Céleste E. Cohen, Dallas M. Swallow, Catherine Walker   +2 more
wiley   +1 more source

Genomic Anomaly Detection with Functional Data Analysis. [PDF]

Genes (Basel)
Kanjilal R, Campelo Dos Santos AL, Arnab SP, DeGiorgio M, Assis R.   +4 more
europepmc   +1 more source

Opportunities and Challenges of Population Pharmacogenomics

Annals of Human Genetics, EarlyView.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou, Yoomi Park, Mahamadou D. Camara, Volker M. Lauschke   +3 more
wiley   +1 more source

Evaluating Genetic Diversity and Regional Variation in Tswana Goats of Botswana. [PDF]

Genes (Basel)
Chalebgwa AB, Monau PI, Raphaka K, Hadebe K, Kgwatalala P, Nsoso SJ.   +5 more
europepmc   +1 more source

Recent Statistical Innovations in Human Genetics

Annals of Human Genetics, EarlyView.
ABSTRACT We review three areas of human genetics that have been developed in the past few decades, in which statistical innovation has made a crucial contribution with recent important advances and the potential for further rapid progress. The first topic is the development of mathematical models for the genealogy underlying samples of genome‐wide ...
David J. Balding, Doug Speed
wiley   +1 more source