Results 251 to 260 of about 292,143 (332)

Gene–Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies

open access: yesAllergy, EarlyView.
Atopic eczema is a complex trait resulting from multiple genetic and environmental factors. This study investigated evidence for interaction between 24 established eczema genetic risk variants and 18 environmental factors. One variant‐environmental pair showed nominally significant interaction in discovery, replication and meta‐analyses: early‐life dog
Marie Standl   +77 more
wiley   +1 more source

Pharmacogenetics of follicle‐stimulating hormone action in the male

open access: yesAndrology, EarlyView.
Abstract Male factor infertility (MFI) is involved in half of the cases of couple infertility. The follicle‐stimulating hormone (FSH) therapy is considered efficient to improve semen parameters and pregnancy rate in patients with idiopathic MFI, following the lesson learned from hypogonadotropic hypogonadism.
Andrea Graziani   +7 more
wiley   +1 more source

Meta‐Analysis: Effects of Steatotic Liver Disease‐Associated Genetic Risk Alleles on Longitudinal Outcomes

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Genetic variants associated with risk of steatotic liver disease (SLD) may also influence clinical events. A systematic review and meta‐analysis consisting of 288,423 patients across 40 studies found that variants in PNPLA3, TM6SF2 and MBOAT7 are significantly associated with hepatic outcomes, with modest effects on extrahepatic outcomes.
Matthew Kubina   +15 more
wiley   +1 more source

Benign polymorphisms in the BRCA genes with linkage disequilibrium is associated with cancer characteristics. [PDF]

open access: yesCancer Sci
Lee KT   +8 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy