Results 261 to 270 of about 308,435 (331)

Genetic risk factor identification for common epilepsies guided by integrative omics data analysis

Epilepsia, EarlyView.
Abstract Objective Genetic generalized epilepsies (GGEs) comprise the most common genetically determined epilepsy syndromes, following a complex mode of inheritance. Although many important common and rare genetic factors causing or contributing to these epilepsies have been identified in the past decades, many features of the genetic architecture are ...
Ashwini Mushunuri, Oluyomi Adesoji, Roland Krause, Patrick May, Holger Lerche, Albert Becker, Daniela Grimm, International League Against Epilepsy Consortium on Complex Epilepsies, Michael Nothnagel, Herbert Schulz   +9 more
wiley   +1 more source

Mining SNP loci and candidate genes for sheath blight resistance in <i>Indica</i> rice using genome-wide association studies. [PDF]

Front Plant Sci
Gu X, Ding J, Xu H, Liu W, Wu H, Tang Q, Yang S, Wang L, Zhang S, Chen L, Meng X, Tao Y, Hao J, Chen Z, Jiang S, Yu R, Xu L, Hassan MA.   +17 more
europepmc   +1 more source

Exonic Variation in HLA‐C, CFB, and TAP2 Associated With Increased Risk for Comorbid Crohn's Disease and Psoriasis

International Journal of Dermatology, EarlyView.
Our recent work established an association between high polygenic risk scores (PRSes) for both psoriasis and Crohn's disease with the development of comorbid disease. The protein‐coding genetic variation associated with the development of comorbid psoriasis and Crohn's disease is understudied.
Vikram R. Shaw, Jinyoung Byun, Catherine Zhu, Jared Sninsky, Younghun Han, Jeffrey M. Cohen, Christopher I. Amos   +6 more
wiley   +1 more source

Population-Based Genetic Assessment of Thrombophilia Polymorphisms: Allelic Frequencies and Population Linkage Dynamics. [PDF]

Medicina (Kaunas)
Tsiatsiou P, Balaska S, Tsinaris Z, Archonti M, Lanta A, Tsaireli V, Takardaki A, Kourti A, Kassomenaki A, Meletis G, Tsakiris DA, Skoura L.   +11 more
europepmc   +1 more source

Genetic crossroads of cardiovascular disease and its comorbidities: toward holistic therapeutic strategies. [PDF]

BMC Med Genomics
Mishra BH, Mishra PP.
europepmc   +1 more source

Moral Distress Among Family Caregivers: A Concept Analysis

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To examine and define the concept of moral distress among family caregivers by identifying its key attributes, antecedents and consequences. Design Concept analysis. Methods This study was guided by Walker and Avant's concept analysis framework.
Tharaa Ananzeh, Caroline F. Morrison, Elaine L. Miller, Natalie Kreitzer, Tamilyn Bakas   +4 more
wiley   +1 more source

Investigating the Causal Relationship and Shared Genetic Basis Between Major Depression Disorder and Eight Types of Gastrointestinal Diseases. [PDF]

Genet Res (Camb)
Sun F, Li H, Gong B, Hui S, He R, Yu M, Li Y, Yang S, Huang P.   +8 more
europepmc   +1 more source

Genomic Prediction Ability for Novel Profitability Traits Using Different Models in Nelore Cattle

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT The aim of this study was to assess the accuracy, bias and dispersion of genomic predictions for accumulated profitability (APF) and profit per kilogram of liveweight gain (PFT) in Nelore cattle using different prediction approaches. The dataset consisted of 3969 phenotypic records for each trait. The pedigree harboured information from 38,930
Letícia Silva Pereira, Cláudio Ulhôa Magnabosco, Guilherme Rosa, Nedenia Bonvino Stafuzza, Tiago Zanett Albertini, Minos Carvalho, Raysildo Barbosa Lobo, Elisa Peripolli, Eduardo da Costa Eifert, Fernando Baldi   +9 more
wiley   +1 more source

Lack of genetic correlation and causal association between specific gut microbiota and osteoporosis. [PDF]

Medicine (Baltimore)
Chen D, Zhu T, Liu C, Zhang Y, Wu Y, Xiong Z, Sun J, Zhang W.   +7 more
europepmc   +1 more source

Single‐Step Genomic Predictions for Growth and Carcass Traits in Nordic Charolais and Hereford Cattle

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT In order to investigate the applicability and efficiency of genomic selection for growth and carcass traits in Nordic beef cattle, single‐step genomic BLUP (ssGBLUP) was applied in 4321 Charolais and 4532 Hereford animals with information on approximately 43,000 SNPs each.
Anahit Nazari‐Ghadikolaei, Freddy Fikse, Susanne Eriksson   +2 more
wiley   +1 more source