Results 31 to 40 of about 290,563 (234)

Complementary multi‐omics profiling of chronic thromboembolic pulmonary hypertension reveals immune cell alterations, epigenetic changes, and genetically supported candidate genes

Animal Models and Experimental Medicine, EarlyView.
This study presents an integrative multi‐omics framework to uncover the molecular mechanisms and potential biomarkers of chronic thromboembolic pulmonary hypertension (CTEPH). Anthropometric and biochemical data were correlated using canonical correlation analysis, revealing key cardiometabolic associations. Single‐cell RNA sequencing identified immune
Xiaopeng Liu, Xia Zheng, Yajun Zhang, Yinghui Fang, Yanan Zhen   +4 more
wiley   +1 more source

Causal connectivity of evolved neural networks during behavior [PDF]

, 2005
To show how causal interactions in neural dynamics are modulated by behavior, it is valuable to analyze these interactions without perturbing or lesioning the neural mechanism.
Anil K. Seth, Bollobás B, Box G EP, Clark A, Edelman G M, Hamilton J D, Kobatake E, McIntosh A R, Newman M EJ, Pearl J, Seth A K, Seth A K, Wiener N   +12 more
core   +1 more source

Genetic prediction of blood cell reactivity and its potential causal influence on bone continuity and density disorders

Animal Models and Experimental Medicine, EarlyView.
We applied Mendelian randomization to explore causal links between blood cell traits and skeletal disorders. Using genetic instruments from large‐scale summary statistics, we assessed effects on bone continuity, density, and structural integrity. Sensitivity and reverse analyses confirmed robust associations, highlighting potential shared biological ...
Zhiqin Deng, Zhe Zhao, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Zhengyang Lin, Zhenhan Deng, Wencui Li   +8 more
wiley   +1 more source

Following people through time : an analysis of individual residential mobility biographies [PDF]

, 2015
Maarten van Ham’s contribution to this research was partly made possible through the financial support of the EU Marie Curie programme under the European Union's Seventh Framework Programme (FP/2007-2013) / Career Integration Grant n.
Coulter, Rory Christopher, Van Ham, Maarten   +1 more
core   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Equilibrium adjustment of disequilibrium prices [PDF]

We consider an exchange economy in which price rigidities are present. In the short run the non-numeraire commodities have a exible price level with respect to the numeraire commodity but their relative prices are mutually fixed.
Herings, P.J.J., Laan, G. van der, Talman, A.J.J., Venniker, R.   +3 more
core   +4 more sources

Error Corrected Disequilibrium [PDF]

We derive an econometric disequilibrium model for time series data. This is done by error correcting the supply of some good. The model naturally separates between a continuously clearing market and a clearing market in the long-run such that we are able
Holmberg, Ulf
core   +1 more source

Genetic Diversity, Adaptation, Wild Introgression, and Coat Color Mutation of Golden Yak

Animal Research and One Health, EarlyView.
Genetic diversity, adaptation, wild introgression, and coat color mutation of golden yak from two populations on the Qinghai‐Xizang Plateau. ABSTRACT The golden yak lives on the Qinghai‐Xizang Plateau with a golden coat and adapts to high altitudes and strong ultraviolet environment. The golden coat is a prominent phenotype in many domesticated species,
Huixuan Yan, Jialei Chen, Chuzhao Lei, Fengwei Zhang, Shunzhong He, Weiru Song, Hongyan Ma, Shuling Li, Guomei Li, Laba Yongcuo, Jianlin Han, Johannes A. Lenstra, Qiang Zhang, Rende Song, Basang Wangdui, Ningbo Chen   +15 more
wiley   +1 more source

A Monetary Approach to the Analysis of Inflation in Ireland [PDF]

This paper formulates a simple monetary model to analyse the role of money in the determination of inflation in Ireland. The model suggests that monetary disequilibrium can affect inflation directly via the exchange rate and indirectly by increasing the ...
Kenny, Geoff, McGettigan, Donal
core  

Population genetics of trypanosoma brucei rhodesiense: clonality and diversity within and between foci [PDF]

, 2013
African trypanosomes are unusual among pathogenic protozoa in that they can undergo their complete morphological life cycle in the tsetse fly vector with mating as a non-obligatory part of this development.
A MacLeod, A MacLeod, A MacLeod, A Tait, A Tait, A Tait, A Tait, Andy Tait, Anneli Cooper, Annette MacLeod, BG Spratt, C. Michael R. Turner, CA Oura, Craig W. Duffy, CW Duffy, Daniel K. Masiga, DK Howe, EM Fevre, EM Fevre, F Balloux, F Mathieu-Daude, F Njiokou, FG Razakandrainibe, G Hide, G Hide, G Hide, HK Auty, HV Xong, J Maynard Smith, J Sternberg, Jeremy Sternberg, JJ McNamara, JR Stevens, L Berrang-Ford, L Jenni, L MacLean, L MacLean, L Peacock, L Peacock, Liam J. Morrison, Lindsay Sweeney, LJ Morrison, LJ Morrison, LJ Morrison, LJ Morrison, LM MacLean, Lorna MacLean, M Koffi, M Koffi, M Tibayrenc, M Tibayrenc, M Tibayrenc, NE Anderson, O Balmer, P Paindavoine, R Peakall, RD Page, RE Paul, RJ Pearce, SC Welburn, TJ Anderson, V Jamonneau, W Gibson, W Gibson, W Gibson, W Gibson, W Gibson, W Weir, WC Gibson, WC Gibson, Z Annan   +70 more
core   +6 more sources