Results 131 to 140 of about 243,630 (312)

Multiparametric Bioresorbable Sensor for Doxorubicin Detection via Molecularly Imprinted Synthetic Receptors

Advanced Science, EarlyView.
A biodegradable molecularly imprinted polymer porous silica sensor enables dual optical readout of doxorubicin via fluorescence and effective optical thickness shifts. The combined transduction mechanisms provide enhanced reliability and quantitative accuracy over clinically relevant concentrations, representing a step toward transient implantable ...
Martina Corsi, Tiziano Di Giulio, Eleonora Vandini, Muhammad Ibrar Asif, Eleonora Daini, Antonietta Vilella, Giuseppina Leo, Alessandra Ottani, Cosimino Malitesta, Daniela Giuliani, Elisabetta Mazzotta, Giuseppe Barillaro   +11 more
wiley   +1 more source

Development and optimization of disinfection protocol for negative pressure wards: a Delphi study

BMC Infectious Diseases
Background Negative pressure wards are used to admit patients with respiratory infectious diseases. Most of the negative pressure wards are currently reconstructed, and the standard disinfection protocol has not yet been established.
Tingting Li, Huilan Zhang, Hongxia Luo, Kunmei Li, Niyan Huang, Sha Yang, Jianping You   +6 more
doaj   +1 more source

Smartly Assembled near‐Micron RF‐Responsive Agents Bridge Transarterial Embolization and Immunothermal Potentiation

Advanced Science, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) remains a significant clinical challenge due to the limited efficacy of conventional treatments like surgery, radiofrequency ablation (RFA), and transarterial embolization (TAE). Here, we develop an innovative TAE and immunothermal therapy strategy based on smartly assembled near‐micron layered double hydroxide ...
Qitao Hu, Junkang Ding, Lingxiao Zhang, Zhou Tian, Cheng Zeng, Shaomin Zou, Wenjing Zhang, Tangye Zeng, Zhencang Gao, Zhouyi Sun, Gang Liu, Weiyu Chen, Zhe Tang   +12 more
wiley   +1 more source

F1534S kdr mutation drives the geographical heterogeneity of pyrethroid resistance in Aedes albopictus from Hangzhou, China

Frontiers in Cellular and Infection Microbiology
IntroductionThe rapid evolution of insecticide resistance in mosquitoes has substantially compromised control efficacy against Aedes albopictus. This study aimed to evaluate the resistance levels to commonly used insecticides in field populations of Ae ...
Binbin Jin, Binbin Jin, Jiawen Du, Lingya Wei, Tianxiao Duan, Jiabao Xu, Yinghong Wang, Ye Lu, Hui Jin, Hui Jin   +9 more
doaj   +1 more source

Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes

Advanced Science, EarlyView.
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang, Ning Lu, Xin‐Xiu Lin, Xu‐Hui Fang, Yi‐Hui Li, Qing‐Peng Luo, Yu‐Ting Peng, Gil Mor, Ai‐Hua Liao   +8 more
wiley   +1 more source

Progress in the application of new ultraviolet disinfection technology

Shanghai yufang yixue
With the pandemic of COVID-19, the World Health Organization warns that disease X is on the verge of a global outbreak, and the problem of multidrug-resistant bacterial infections in medical and healthcare institutions becomes more serious. Compared with
ZHU Renyi, ZHANG Yucheng, TIAN Liang
doaj   +1 more source

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

Advanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng, Jiahao Lin, Qiushuang Zhang, Xiangdong Zhang, Yicong Dai, Jinghong Li   +5 more
wiley   +1 more source

Chitosan‐Carbon Dot Composite Materials Form a Leaf Surface Barrier to Mitigate the Enrichment and Invasion of Nanoplastics: From Leaf Interface to Systemic Response

Advanced Science, EarlyView.
Foliar spraying of CS‐CDs can form a film on the leaves of Brassica rapa, effectively reducing the enrichment and absorption of PS in the leaves, while increasing the biomass and nutrient content of the plants. In addition, CS‐CDs can also enrich the interfoliar microbial community and activate the plant's own defense metabolic pathways.
Beibei Zhao, Mei Li, Mengjiao Fan, Chuanhuan Liu, Jie Jiang, Jia Song, Yingzhu Liu   +6 more
wiley   +1 more source

Detection of DENV in Aedes albopictus during the 2024 sporadic dengue outbreak in Wuhan city, Hubei Province, China

Virology Journal
From September to October 2024 in Wuhan, three indigenous dengue cases were reported in Wuhan for the first time since the 1940s. Here, we report the results of the epidemiological investigation of the sporadic dengue outbreak and the detection of dengue
Liqun Wu, Yijie Zhang, Zhi Chen, Banghua Chen, Manqing Liu, Weifeng Tang, Feng Pan, Wenhua Kong, Yixuan Wu, Xiaomin Chen   +9 more
doaj   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

Advanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang, Tong Dou, Luokai Wang, Jingxian Yang, Wenrui Wang, Shuaitian Guo, Xiangyu Li, Xuefang Huang, Yunlei Xianyu, Dongsheng Wang   +9 more
wiley   +1 more source