Results 111 to 120 of about 2,014,535 (251)
A Baire Category Approach to Rounded Discrete Max Domains of Attraction
MathematicsWe study a topological problem in discrete extreme value theory. Let P(N) denote the space of probability laws on N, endowed with the total variation metric dTV. Fix a rounding map r, either the ceiling map or the nearest-integer map.
Malick Kebe, Ashley Oaks, Demba Sy
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Licensing Reflexivity: Unity and variation among selected Uralic languages [PDF]
, 2014 This dissertation analyzes the reflexivity patterns in Uralic languages from the point of view of a minimalist approach to binding. The languages under consideration are five Uralic languages spoken in the Russian Federation: Meadow Mari, Komi-Zyrian ...
Volkova, A.A. +3 more
core
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
The two-disjoint-cycle-cover pancyclicity of locally twisted cubes
, 2013 [[abstract]]In this paper, a graph G is two-disjoint-cyclecover r-pancyclic if for any integer l satisfying r ? l ? |V (G)|?r, there exist two vertex-disjoint cycles C1 and C2 in G such that the lengths of C1 and C2 are l and |V (G)|?l, respectively ...
Kung, Tzu-Liang;Chen, Hon-Chan
core
FEBS Open Bio, EarlyView.Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
The Two-Disjoint-Path-Coverable Problem of Crossed Cubes
, 2013 [[abstract]]A graph G is 2-disjoint-path-coverable (2-DPC) if, for any four distinct vertices u, v, x, and y of G, there exist two vertex-disjoint paths P1 and P2 such that (i) P1 joins u and v, (ii) P2 joins x and y, and (iii) P1 ∪ P2 spans G.
Chen, Hon-Chan;Kung, Tzu-Liang;Hsu, Li-Yen
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk +10 more
wiley +1 more source