Results 31 to 40 of about 214,122 (269)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Investigation of the dragging stress of aluminium under cyclic loading

open access: yesMechanical Engineering Journal
The effect of the variation of the dislocation velocity on the dragging stress of aluminium under cycling loading has been investigated. Hydrogen diffusion around a dislocation was simulated by the finite difference method, and the dragging stress was ...
Shota HASUNUMA, Tomoyuki HAYASE
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

How to Rescue of the Dislocated XEN® Gel Stent: A New Surgical Approach on XEN Dislocation and Narrative Review

open access: yesJournal of Current Ophthalmology
Purpose: To introduce a novel surgical technique for repositioning a dislocated XEN63® gel stent in patients with open-angle glaucoma, to synthesize contemporary findings on complications associated with stent dislocation, and to comment on related ...
Vincenzo Marchese   +3 more
doaj   +1 more source

Uncommon Dorsal Radiocarpal Fracture Dislocation Complicated With Median Nerve Palsy: Case Report, Review of the Literature, and a New Classification System Guiding the Management

open access: yesJournal of Orthopaedics, Trauma and Rehabilitation, 2012
We report the case of a 36-year-old lorry driver who sustained left dorsal radiocarpal fracture dislocation and left median nerve injury in a traffic accident in 2010.
Hing-Cheong Wong   +2 more
doaj   +1 more source

Traumatic sternoclavicular joint dislocation - A case series and discussion of methods of management

open access: yesJournal of Orthopaedic Diseases and Traumatology, 2022
Traumatic sternoclavicular (SC) joint injuries account for
V N Ravish   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Physical Therapy in the Recovery of Young Fighters with Primary Shoulder Dislocation

open access: yesACROSS, 2022
The interest and desire to practice wrestling among adolescents and young people in our republic is quite high. The large number of those who practice sports activities increases the incidence of trauma suffered in practical lessons, training and sports
A.I. POSTOLACHI   +2 more
doaj  

PVNS or pseudo aneurysm: MRI-problem solving or misleading?

open access: yesIndian Journal of Radiology and Imaging, 2015
Pigmented villonodular synovitis (PVNS) is a benign neoplastic process affecting the synovium.Magnetic resonance imaging (MRI) is considered as the imaging modality of choice, where PVNS is seen as a soft tissue lesion affecting the synovium with ...
Bhagya Sannananja   +3 more
doaj   +1 more source

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