Results 41 to 50 of about 334,841 (309)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigation of the dragging stress of aluminium under cyclic loading
Mechanical Engineering JournalThe effect of the variation of the dislocation velocity on the dragging stress of aluminium under cycling loading has been investigated. Hydrogen diffusion around a dislocation was simulated by the finite difference method, and the dragging stress was ...
Shota HASUNUMA, Tomoyuki HAYASE
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A unified model for dislocation nucleation, dislocation emission and dislocation free zone
, 1996 In this paper, a unified model for dislocation nucleation, emission and dislocation free zone is proposed based on the Peierls framework. Three regions are identified ahead of the crack tip.
张永伟 +3 more
core +1 more source
Journal of Current OphthalmologyPurpose: To introduce a novel surgical technique for repositioning a dislocated XEN63® gel stent in patients with open-angle glaucoma, to synthesize contemporary findings on complications associated with stent dislocation, and to comment on related ...
Vincenzo Marchese +3 more
doaj +1 more source
Journal of Orthopaedics, Trauma and Rehabilitation, 2012 We report the case of a 36-year-old lorry driver who sustained left dorsal radiocarpal fracture dislocation and left median nerve injury in a traffic accident in 2010.
Hing-Cheong Wong +2 more
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Traumatic sternoclavicular joint dislocation - A case series and discussion of methods of management
Journal of Orthopaedic Diseases and Traumatology, 2022 Traumatic sternoclavicular (SC) joint injuries account for
V N Ravish +4 more
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Physical Therapy in the Recovery of Young Fighters with Primary Shoulder Dislocation
ACROSS, 2022 The interest and desire to practice wrestling among adolescents and young people in our republic is quite high. The large number of those who practice sports activities increases the incidence of trauma suffered in practical lessons, training and sports
A.I. POSTOLACHI +2 more
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