Results 61 to 70 of about 334,841 (309)

Microstructures Evolution in Refill Friction Stir Spot Welding of Al-Zn-Mg-Cu Alloy

open access: yesMetals, 2020
In this study, Al-Zn-Mg-Cu alloy was refill friction spot welded, and the precipitates, dislocation, recovery, and recrystallization characteristics were focused. In the stir zone (SZ), continues dynamic recrystallization occurs under the intense plastic
Yunqiang Zhao   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Irreducible Traumatic Posterior Shoulder Dislocation [PDF]

open access: yes, 2017
History of present illness: A 22-year-old male presented to the Emergency Department complaining of right shoulder pain after a motocross accident.
Trigger, Christopher   +4 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Dynamic Shear Deformation in Zinc Crystals [PDF]

open access: yes, 1962
The initial stages of yielding in single crystals of zinc have been investigated at temperatures of -292°F (-180°C), -93°F (-70°C) and +75°F (24°C), by means of rapidly applied constant stress pulses to produce slip along the basal planes of these ...
King, Kenneth Robert
core   +1 more source

Asymptomatic Chronic Dislocation of a Cemented Total Hip Prosthesis

open access: yesWestern Journal of Emergency Medicine, 2014
[West J Emerg Med. 2014;15(1):107–108.]
Andrea Emilio Salvi   +2 more
doaj   +1 more source

Bilateral Asymmetrical Fracture Dislocation of Shoulder with Rare Combination of Injuries after Epileptic Seizure: A Case Report [PDF]

open access: yesMalaysian Orthopaedic Journal, 2017
The incidence of bilateral gleno-humeral joint dislocation is rare, is almost always posterior and is usually caused by sports injuries, epileptic seizures, electrical shock, or electroconvulsive therapy.
Sharma A   +4 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

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