Results 81 to 90 of about 334,841 (309)

Topological events on wave dislocation lines: birth and death of small loops, and reconnection

open access: yes, 2007
In three-dimensional space, a wave dislocation, that is, a quantized (optical) vortex or phase singularity, is a line zero of a complex scalar wavefunction.
Dennis, MR   +5 more
core   +1 more source

Recurrent bilateral TMJ dislocation in a 20-month-old child: A rare case presentation

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2011
Temporomandibular joint dislocations are extremely rare in children and only four such cases have been reported in the literature so far. However, a case of recurrent bilateral mandibular dislocation is even rare to occur and a report of one such case is
S Chhabra, N Chhabra
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

SOME CONSIDERATIONS ON DISLOCATION FOR THERMOELASTIC MICROSTRETCH MATERIALS [PDF]

open access: yesAnnals: Series on engineering sciences (Academy of Romanian Scientists), 2013
The aim of our study is to derive a relation of De Hoop-Knopoff type for displacement fields within the context of thermoelastic microstretch bodies. Then, as a consequence, an explicit expression of the body loadings equivalent to a seismic dislocation,
Marin MARIN, Olivia FLOREA
doaj  

Comparison of Procedural Sedation for the Reduction of Dislocated Total Hip Arthroplasty

open access: yesWestern Journal of Emergency Medicine, 2014
Introduction: Various types of sedation can be used for the reduction of a dislocated total hip arthroplasty. Traditionally, an Opiate/Benzodiazepine combination has been employed.
Jonathan E. dela Cruz   +8 more
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Lower nanometer-scale size limit for the deformation of a metallic glass by shear transformations revealed by quantitative AFM indentation

open access: yesBeilstein Journal of Nanotechnology, 2015
We combine non-contact atomic force microscopy (AFM) imaging and AFM indentation in ultra-high vacuum to quantitatively and reproducibly determine the hardness and deformation mechanisms of Pt(111) and a Pt57.5Cu14.7Ni5.3P22.5 metallic glass with ...
Arnaud Caron, Roland Bennewitz
doaj   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

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