Results 101 to 110 of about 7,286,183 (302)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Dislocation-density function dynamics - An all-dislocation, full-dynamics approach for modeling intensive dislocation structures

, 2016
It has long been recognized that a successful strategy for computational plasticity will have to bridge across the meso scale in which the interactions of high quantities of dislocations dominate.
Ngan, AHW, Ngan, A. H.W., LEUNG, HS, Leung, H. S.   +3 more
core   +1 more source

Characterizing the Substructural Changes in Metals by Microindentation and Various Numerical Approaches

Metals
This contribution compares various theories dealing with the assessment of dislocation density in metals subjected to different straining levels. The paper examines both substructure development and the evolution of dislocation densities in 1xxx, 5xxx ...
János György Bátorfi, Jurij J. Sidor
doaj   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

Simulation of screw dislocations in wadsleyite [PDF]

, 2010
The structure and energies of the cores of [100] and [001] screw dislocations in wadsleyite \left(\beta-Mg{_2}SiO{_4}\right) are calculated using a cluster-based combined elastic-atomistic method and a new parameterized interatomic potential model.
Walker, AM, Walker, A.M.
core   +1 more source

Segregation-dislocation self-organized structures ductilize a work-hardened medium entropy alloy

Nature Communications
Dislocations are the intrinsic origin of crystal plasticity. However, initial high-density dislocations in work-hardened materials are commonly asserted to be detrimental to ductility according to textbook strengthening theory.
Bojing Guo, Ding-Cong Cui, Qing-Feng Wu, Yuemin Ma, Daixiu Wei, K. R., Ya-Shan Zhang, Chenbo Xu, Zhi-Jun Wang, Jun-Jie Li, Xin Lin, Jin-Cheng Wang, Xun-Li Wang, F. He   +13 more
semanticscholar   +1 more source

The Use of Ultrasound to Measure Dislocation Density [PDF]

, 2015
Artículo de publicación ISIDislocations are at the heart of the plastic behavior of materials yet they are very difficult to probe experimentally. Lack of a practical nonintrusive measuring tool for, say, dislocation density, seriously hampers modeling ...
Lund Plantat, Fernando, Maurel, Agnès, Barra de La Guarda, Felipe, Barra, Felipe, Pagneux, Vincent, Espinoza-González, Rodrigo, Lund, Fernando, Fernández, Henry, Espinoza González, Rodrigo   +8 more
core   +1 more source

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

Advanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth, Tomáš Babinský, Jan Lars Riedel, Wen Hao Kan, Aijun Huang, Martin Heilmaier, Ivo Šulák   +6 more
wiley   +1 more source

Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows

Advanced Engineering Materials, EarlyView.
A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba, Sang‐Hyeok Lee, Christina Gasper, Martina Freund, Sandra Korte‐Kerzel, Ulrich Kerzel   +5 more
wiley   +1 more source

Quantitative evaluation of dislocation density in SUS316L utilizing non-contact microwave reflection method

Mechanical Engineering Journal
Metallic materials are widely employed due to their exceptional mechanical attributes. Plastic deformation is a common issue that influences both the mechanical and electrical properties, with profound implications for the longevity of engineered ...
Guodong WANG, Shaojie GU, Yasuhiro KIMURA, Yuhki TOKU, Yang JU   +4 more
doaj   +1 more source