Results 81 to 90 of about 386,467 (345)

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Enhancing mechanical and tribological properties of laser-based directed energy deposited IN718 alloy via synchronised high repetition laser shock peening

Virtual and Physical Prototyping
Laser-based direct energy deposition (LDED) has been restricted by unavoidable defects and poor mechanical performance. This study proposes synchronised high repetition laser shock peening (HRLSP) to modify the mechanical and tribological properties of ...
Jiantao Zhou, Qingpeng Chen, Xu Han, Sheng Liu   +3 more
doaj   +1 more source

The MMP‐9/TIMP‐1 Ratio and Concentrations of Osteopontin Are Elevated in Cerebrospinal Fluid of People With Multiple Sclerosis and Decrease After Autologous Hematopoietic Stem Cell Transplantation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the utility of cerebrospinal fluid (CSF) biomarkers—matrix metalloproteinase‐9 (MMP‐9), tissue inhibitor of metalloproteinases‐1 (TIMP‐1), the MMP‐9/TIMP‐1 ratio, and osteopontin (OPN)—as indicators of blood–brain barrier (BBB) integrity and disease activity in people with relapsing–remitting multiple sclerosis (pwMS ...
Ivan Pavlovic, Ida Erngren, Kim Kultima, Anders Larsson, Malin Müller, Anna Wiberg, Joachim Burman   +6 more
wiley   +1 more source

Microstructural Evolution and Tensile Properties of Nb-V-Ti-N Microalloyed Steel with Varying Nitrogen Contents

Metals
With the rapid development of long-distance transmission pipelines for oil and natural gas, pipeline steel is continuously evolving towards higher pressure, larger diameter, and thicker wall thickness.
Jiangcheng Liu, Kai Guo, Haote Ma, Jiangli He, Junchao Wang, Chuanyou Zhang, Tiansheng Wang, Qingfeng Wang   +7 more
doaj   +1 more source

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih, Sara Samadzadeh, Charlotte Bereuter, Seyedamirhosein Motamedi, Claudia Chien, Pablo Villoslada, Hadas Stiebel‐Kalish, Nasrin Asgari, Yang Mao‐Draayer, Marius Ringelstein, Joachim Havla, Marco Aurélio Lana Peixoto, Ho Jin Kim, Jacqueline Palace, Maria Isabel Leite, Srilakshmi M. Sharma, Fereshteh Ashtari, Rahele Kafieh, Lekha Pandit, Orhan Aktas, Philipp Albrecht, Letizia Leocani, Itay Lotan, Sasitorn Siritho, Jérôme de Seze, Romain Marignier, Caroline Froment Tilikete, Denis Bernardi Bichuetti, Ivan Maynart Tavares, Ayse Altintas, Anu Jacob, Saif Huda, Ibis Soto de Castillo, Lawrence J. Cook, Michael R. Yeaman, Axel Petzold, Alexander U. Brandt, Friedemann Paul, Frederike C. Oertel, Hanna G. Zimmermann, with the Guthy Jackson Charitable Foundation—International Clinical Consortium and CROCTINO Collaborators   +40 more
wiley   +1 more source

Evolution of tribo-magnetization during sliding of ferromagnetic materials

Friction
Sliding-induced subsurface microstructure evolution is believed to be decisive for determining the friction and wear performance of metallic contacts as well as the development of tribo-magnetization.
Fumin Gao, Laibin Zhang, Jin Zhou, Yi Xiong, Jing Wu, Jianchun Fan   +5 more
doaj   +1 more source

Fatigue crack growth characteristics of Fe and Ni under cyclic loading using a quasi-continuum method

Beilstein Journal of Nanotechnology, 2018
A quasi-continuum (QC) method based on the embedded atom method (EAM) potential was employed to investigate the fatigue crack growth and expansion characteristics of single-crystal Fe and Ni under cyclic loading modes I and II.
Ren-Zheng Qiu, Yi-Chen Lin, Te-Hua Fang
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Ti3C2Tx MXene‐Zirconium Diboride Based Ultra‐High Temperature Ceramics

Advanced Science
MXenes are a family of two‐dimensional (2D) transition metal carbides, nitrides, and carbonitrides with potential applications in ceramics and composites due to their nanometer‐thick morphology, hydrophilic surfaces, and negative zeta potentials. In this
Srinivasa Kartik Nemani, Nicola Gilli, Steven Goldy, Ankit Kumar, Yooran Im, Austin J. Vorhees, Brian C. Wyatt, Nithin Chandran BS, Nikhilesh Chawla, Garritt J. Tucker, Laura Silvestroni, Babak Anasori   +11 more
doaj   +1 more source

Plasticity-mediated collapse and recrystallization in hollow copper nanowires: a molecular dynamics simulation

Beilstein Journal of Nanotechnology, 2016
We study the thermal stability of hollow copper nanowires using molecular dynamics simulation. We find that the plasticity-mediated structural evolution leads to transformation of the initial hollow structure to a solid wire.
Amlan Dutta, Arup Kumar Raychaudhuri, Tanusri Saha-Dasgupta   +2 more
doaj   +1 more source