Results 61 to 70 of about 94,816 (318)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Analysis on the Key Parameters to Predict Flow Stress during Ausforming in a High-Carbon Bainitic Steel

Metals, 2023
Since flow stress is an important parameter in the processing and application of metallic materials, it is necessary to trace the flow stress during austenite deformation. Thermal compression deformation of austenite in a high-strength bainitic steel was
Lifan Wang, Haijiang Hu, Wei Wang, Ping He, Zhongbo Li, Guang Xu   +5 more
doaj   +1 more source

Supplemental_Table_1 – Supplemental material for Dorsal Wrist Spanning Plate Fixation for Treatment of Radiocarpal Fracture-Dislocations

, 2019
Supplemental material, Supplemental_Table_1 for Dorsal Wrist Spanning Plate Fixation for Treatment of Radiocarpal Fracture-Dislocations by Elizabeth P. Wahl, Alexander S. Lauder, Tyler S. Pidgeon, Evan M. Guerrero, David S. Ruch and Marc J.
Alexander S. Lauder (8155023), Elizabeth P. Wahl (8155020), David S. Ruch (8155032), Marc J. Richard (8155035), Evan M. Guerrero (8155029), Tyler S. Pidgeon (8155026)   +5 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Driving dislocations in graphene

, 2012
Electron microscopy has revealed time-resolved glide and climb motion of dislocations in graphene and imaged their strain and rotation fields.Depto. de Análisis Matemático y Matemática AplicadaFac.
Bonilla, Luis L., Carpio Rodríguez, Ana María   +1 more
core   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Review of Non-Classical Features of Deformation Twinning in hcp Metals and Their Description by Disconnection Mechanisms

Metals, 2020
The study of deformation twinning has long history. However new, sometimes surprising, findings have shown that the phenomenon of deformation twinning still is not completely understood.
Andriy Ostapovets, Anna Serra
doaj   +1 more source

Strengthening of an Al-Cu-Mg alloy processed by high-pressure torsion due to clusters, defects and defect-cluster complexes [PDF]

, 2015
A physically-based model is established to predict the strength of cluster strengthened ultrafine-grained ternary alloys processed by severe plastic deformation. The model incorporates strengthening due to dislocations, grain refinement, co-clusters (due
Sha, Gang, Chen, Ying, Ringer, Simon P., Starink, Marco J., Gao, Nong   +4 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source