Results 21 to 30 of about 359,449 (281)

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders [PDF]

, 2022
BACKGROUND: Sex differences in incidence and/or presentation of schizophrenia (SCZ), major depressive disorder (MDD), and bipolar disorder (BIP) are pervasive.
Gejman V, P., Landen, M., Mayoral, F., Air, T., Rujescu, D., Tiemeier, H., Cairns, M., Grabe, H., Boomsma, D., der Auwera, S., Sham, P., Jonsson, E., Hottenga, J., Mowry, B., Boomsma I, D., Lencz, T., Mehta, D., Blokland, G., Tooney, P., McIntosh, A., Nordentoft, M., Uher, R., Etain, B., Bellivier, F., Smeland, O., Ehrenreich, H., Lucae, S., Konte, B., Mors, O., Cichon, S., Vincent, J., Gejman, P., Forstner, A., Cotsapas, C., Begemann, M., Molden, E., Malhotra, A., Guzman-Parra, J., Leboyer, M., Buxbaum, J., Djurovic, S., Kelly, B., Melle, I., Weissman, M., Hauser, J., Iwata, N., Borglum, A., Chen, C., McQuillin, A., Lissowska, J., Adams, M., Bass, N., Esko, T., Adolfsson, R., Teumer, A., Nothen, M., Wu, J., Knowles, J., Corvin, A., Børglum, A., Volker, U., Muller-Myhsok, B., Milani, L., Hamshere, M., Perlis, R., Weinberger, D., Biernacka, J., Mullins, N., Als, T., Comes, A., Smoller, J., O’Donovan, C., Periyasamy, S., Scott, L., Goldstein, J., O'Donovan, C., Schaupp, S., Willemsen, G., Grove, J., Alda, M., Preisig, M., Mitchell, P., McElroy, S., Lewis, C., Vaaler, A., Breen, G., Streit, F., Świątkowska, B., Jamain, S., Ophoff, R., Penninx, B., St Clair, D., Bramon, E., Hartmann, A., Kirov, G., Murray, R., Rietschel, M., Martin, N., Baune, B., Degenhardt, F., Kogevinas, M., Handa, R., Hougaard, D., Palotie, A., Van der Auwera, S., Tobet, S., Lee, J., Kelsoe, J., Levinson, D., Clair, D., Shi, J., Potash, J., Steixner-Kumar, A., Hamilton, S., Mortensen, P., Frye, M., Sanders, A., Sirignano, L., Viktorin, A., Andreassen, O., Giegling, I., Reif, A., de Geus, E., Fullerton, J., Schofield, P., Grigoroiu-Serbanescu, M., Sullivan, P., Stahl, E., Petryshen, T., Werge, T., Riley, B., Cervantes, P., Magnusson, P., Pato, M., Milaneschi, Y., Schulze, T.   +135 more
core   +3 more sources

Disorders of Sex Development [PDF]

Korean Journal of Urology, 2012
The birth of a new baby is one of the most dramatic events in a family, and the first question is usually "is it a boy or a girl?" The newborn infant with ambiguous external genitalia often comes as a surprise for the doctors as well as the parents and is sometimes described as an endocrine emergency situation presenting a problem of sex assignment ...
Kim, Kun Suk, Kim, Jongwon
  +6 more sources

SRY-Positive 46-XX Testicular Disorder of Sex Development as a Rare Cause of Male Hypergonadotropic Hypogonadism: A Case Report

Endocrinology Research and Practice, 2021
46XX testicular Disorder of Sex Development (DSD) is a rare condition characterized by sexual differentiation disorder with testicular insufficiency. Normal sex development often complicates the diagnosis of this ailment in adults.
Mustafa CAN, Muhammet KOCABAŞ, İlker ÇORDAN, Hatice ÇALISKAN BURGUCU, Melia KARAKÖSE, Mustafa KULAKSIZOĞLU, Feridun KARAKURT   +6 more
doaj   +1 more source

‘It was Supposed to be a Secret’: a study of disclosure and stigma as experienced by adults with differences of sex development

Health Psychology and Behavioral Medicine, 2022
Background Differences of sex development (DSD) are a group of congenital conditions that involve variations in sex chromosomes, genes, external and/or internal genitalia, hormones, and secondary sex characteristics. The present study sought to highlight
Line Merete Mediå, Lena Fauske, Solrun Sigurdardottir, Kristin J. Billaud Feragen, Charlotte Heggeli, Anne Wæhre   +5 more
doaj   +1 more source

Disorders of sex development [PDF]

Best Practice & Research Clinical Obstetrics & Gynaecology, 2018
Normal sex development depends on the precise spatio-temporal sequence and coordination of mutually antagonistic activating and repressing factors. These factors regulate the commitment of the unipotential gonad into the binary pathways governing normal sex development. Typically, the presence of the SRY gene on the Y chromosome triggers the cascade of
  +5 more sources

Vaginoplasty for Disorders of Sex Development [PDF]

Frontiers in Endocrinology, 2013
One of the most common problem found in patients with Disorders of Sexual Developments is the absence or extreme hypoplasia of the vagina. The type of patients presenting this anomaly may belong to completely different groups: (1) Patients with a urogenital sinus with urethra and vagina fusing together to form a common channel. (2) Patients with absent
Nino Guarino, Salvatore Scommegna, Silvia Majore, Anna Maria Rapone, Luciana Ungaro, Aldo Morrone, GRAMMATICO, Paola, Giacinto A. Marrocco   +7 more
openaire   +3 more sources

Patients with disorders of sex development [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2021
Disorders of sex development (DSDs) are a genetically and clinically heterogeneous group of congenital conditions of the urogenital tract and reproductive system. Time and spatially controlled transcription factors, signal molecules, and an array of different hormones are involved in the development of sex characteristics, and variations in their ...
openaire   +3 more sources

Consanguinity and Disorders of Sex Development [PDF]

Human Heredity, 2014
Disorders of sex development (DSD) are defined as 'congenital conditions in which the development of chromosomal, gonadal, or anatomical sex is atypical' [Lee et al., Pediatrics 2006;118:e488-e500]. Studies conducted in Western countries, with low rates of consanguinity, show that truly ambiguous genitalia have an estimated incidence of 1:5,000 births.
Anu, Bashamboo, Ken, McElreavey
openaire   +2 more sources

Quality of Life and Psychological Well-being in Children and Adolescents with Disorders of Sex Development

JCRPE, 2021
Objective:The aim of this study was to assess the quality of life (QoL) and psychological well-being in child and adolescent with disorders of sex development (DSD).Methods:Sixty-two cases, aged 2-18 years, who were followed by a multidisciplinary DSD ...
Birsen Şentürk Pilan, Burcu Özbaran, Didem Çelik, Tuğçe Özcan, Samim Özen, Damla Gökşen, İbrahim Ulman, Ali Avanoğlu, Sibel Tiryaki, Hüseyin Onay, Özgür Çoğulu, Ferda Özkınay, Şükran Darcan   +12 more
doaj   +1 more source

Malignancy in disorders of sex development [PDF]

Translational Andrology and Urology, 2016
Disorders of sex development (DSD) represent a spectrum of conditions in which chromosomal, gonadal, or anatomic sex are atypical and affect 1 in 4,500-5,000 live births. The diagnosis of DSD raises concerns of tumor risk and treatment as well as future fertility preservation.
Kathrins, Martin, Kolon, Thomas F.
openaire   +2 more sources