The epidemiology of disorders of sex development
Best Practice & Research Clinical Endocrinology & MetabolismDuring recent years the epidemiology of disorders of sex development (DSD) has been more clearly delineated. Here, we provide a detailed and up-to-date synopsis of the epidemiology of DSD, incorporating the latest body of knowledge in the field for sex chromosome DSD (Turner, Klinefelter, 47,XXX, and 47,XXY syndrome, and 45,X/46,XY mosaicism) as well ...
Berglund, Agnethe +4 more
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Internet sex addiction: a review of empirical research [PDF]
, 2012 The advent of the internet has added another medium in which people can engage in sexual behaviour. This ranges from the passive consumption of online pornography to the interactive exchange of sexual content in cybersex chat rooms.
Griffiths, MD
core
Epidemiology and heritability of Major Depressive Disorder, stratified by age of onset, sex, and illness course in Generation Scotland:Scottish Family Health Study (GS:SFHS) [PDF]
, 2015 The heritability of Major Depressive Disorder (MDD) has been estimated at 37% based largely on twin studies that rely on contested assumptions. More recently, the heritability of MDD has been estimated on large populations from registries such as the ...
Andrew G. McKechanie (827281) +78 more
core +1 more source
Pregnancy in an SRY-Negative XX Developmental Sex Disorder Pig After Removing an Ovotestis
Veterinary SciencesA 2-year-old Large White research gilt was presented to the Comparative Theriogenology service at WSU for infertility. She was produced from the transfer of genetically modified embryos obtained via in vitro fertilization (IVF) that had been treated with
Jewel Toenges +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Psychiatric morbidity associated with same-sex sexual behaviour: influence of minority stress and familial factors [PDF]
, 2010 Background. Increased psychiatric morbidity has been widely reported among non-heterosexual individuals (defined as reporting a homosexual/bisexual identity and/or same-sex sexual partners).
Frisell, T. +7 more
core +1 more source
Disorder Of Sex Development : Ambiguous Genitalia, Partial Androgen Insensitivity Syndrome
Averrous: Jurnal Kedokteran dan Kesehatan Malikussaleh, 2018 Disorders of sex development (DSDs) also known as “intersex” are congenital condition by mismatch in which chromosomal, gonadal and anatomical. One in 4.500 infants is born with abnormalities of External genitalia, and mostly unexplained in molecular ...
Rajuddin Rajuddin, Fauzan Fauzan
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Psychosocial correlates of recidivism in a sample of ex-prisoners: the role of Oppositional Defiant Disorder and Conduct Disorder [PDF]
, 2014 The present study aimed to (a) examine the role of Oppositional Defiant Disorder and Conduct Disorder in predicting recidivism, while controlling for childhood arrest, perceived neighbourhood crime frequency, alcohol consumption, age, and gender, and (b)
Dhingra, Katie +7 more
core +1 more source