Results 41 to 50 of about 8,346 (254)

Recombinant Human Thrombopoietin Reduces the Need for Platelet Transfusion in Patients With Chronic Liver Disease and Thrombocytopenia

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Chronic liver disease (CLD)‐related thrombocytopenia can limit the feasibility of invasive procedures. Recombinant human thrombopoietin (rhTPO) has demonstrated a favorable safety profile without hepatotoxicity. We evaluated the efficacy and safety of rhTPO in patients with CLD‐related thrombocytopenia who were undergoing elective invasive ...
Yifan Han   +45 more
wiley   +1 more source

Distinct Neuropsychiatric Profiles Associated With 17p11.2 Deletions and RAI1 Variants in Smith–Magenis Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith–Magenis syndrome (SMS) results from either a recurrent 17p11.2 deletion or pathogenic variants in the retinoic acid induced 1 gene (RAI1). While neurodevelopmental impairment and behavioral dysregulation are well recognized, systematic genotype‐stratified analyses across psychiatric domains remain limited.
Albin Blanc   +7 more
wiley   +1 more source

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness   +11 more
wiley   +1 more source

Sleep disorders and posttraumatic stress in raped victims

open access: yesRevista de la Facultad de Medicina, 2012
Objective. To determine sleep disorders and posttraumatic stress symptoms in a group of raped female victims and to assess the causal influence by a survey of the association between exposed and unexposed groups and compare those events.
Franklin Escobar-Córdoba   +2 more
doaj  

The influence of socio-economic status on the severity of obstructive sleep apnea: a cross-sectional observational study [PDF]

open access: yesSleep Science
Objective: There is limited evidence about the effect of socio-economic status (SES) on the severity of obstructive sleep apnea (OSA). We aimed to investigate this relationship in a referral population in Greece, with
Dimitrios Papadopoulos   +3 more
doaj   +1 more source

515 Excessive daytime sleepiness: beyond the Epworth Sleepiness Scale results from a population-based study

open access: yes, 2021
Excessive daytime sleepiness (EDS) is a common symptom present in several clinical, mental and sleep disorders. However, its subjective metrics have been criticized in the literature due to lack of association with disorder severity, or ...
E. Treptow   +7 more
semanticscholar   +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

open access: yesThe Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose   +2 more
wiley   +1 more source

Comparative Analysis of Methods of Evaluating Human Fatigue

open access: yesSleep Science
The present study used four different methods to estimate fatigue. Forty-seven volunteers (45 men and 2 women), 41.3 ± 7.5 years old, truck operators for 11.5 ± 6.0 years, were included.
Marco Túlio de Mello   +6 more
doaj   +1 more source

Excessive daytime sleepiness in nursing technicians: association with sleep quality and memory [PDF]

open access: yesRevista Brasileira de Enfermagem
Objective: to investigate excessive daytime sleepiness prevalence among nursing technicians and the association with sleep quality and memory. Methods: a cross-sectional, inferential study, carried out in a hospital unit in the state of Goiás between ...
Renato Canevari Dutra da Silva   +4 more
doaj   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

open access: yesBiological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater   +12 more
wiley   +1 more source

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