Results 81 to 90 of about 1,089,337 (357)

Sexuality in Adults with Differences/Disorders of Sex Development (DSD): Findings from the dsd-LIFE Study

Journal of Sex & Marital Therapy, 2019
For various reasons, sexuality of individuals with differences/disorders of sex development (DSD) may be affected. The aim of the study was to describe sexual activity, satisfaction with sex life, satisfaction with genital function, and sexual problems ...
B. Kreukels, P. Cohen-Kettenis, R. Roehle, T. C. van de Grift, J. Słowikowska-Hilczer, H. Claahsen-van der Grinten, A. Lindén Hirschberg, A. D. de Vries, N. Reisch, C. Bouvattier, A. Nordenström, U. Thyen, B. Köhler, On Behalf Of The Dsd-Life Group   +13 more
semanticscholar   +1 more source

Human sex development: targeted technologies to improve diagnosis [PDF]

, 2016
A new study of disorders of sex development presents an improved targeted next-generation sequencing approach for their ...
Achermann, JC, Buonocore, F
core   +3 more sources

Mental, behavioral and neurodevelopmental disorders in the ICD-11 : An international perspective on key changes and controversies [PDF]

, 2020
The Author(s). 2020Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, andreproduction in any ...
Berk, Michael, Brewin, Chris, Briken, Peer, Cohen-Kettenis, Peggy T, de Jonge, Peter, de Vries, Ymkje Anna, Fineberg, Naomi, Gaebel, Wolfgang, Grilo, Carlos M, Maercker, Andreas, Maj, Mario, Pike, Kathleen, Reed, Geoffrey M., Roest, Annelieke, Stein, D.J., Szatmari, Peter, Vieta, Eduard   +16 more
core   +9 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

46,XY ovotesticular disorders of sex development: A therapeutic challenge

Pediatric Reports, 2017
46,XY ovotesticular disorder of sex development is extremely rare and indicates the presence of both testis and ovary in the same patient. Gender assignment in newborns represents a therapeutic challenge.
Maria-Grazia Scarpa, Massimo Di Grazia, Gianluca Tornese   +2 more
doaj   +1 more source

Unravelling complex mosaicism of sex chromosomes in a patient with primary amenorrhea through cytogenetic analysis on urothelial cells

Taiwanese Journal of Obstetrics & Gynecology, 2021
Objective: Sex chromosome mosaicism remains challenging in the study of disorders of sex development (DSD). Aneuploid cells in the developing gonad play a major role in sex determination. Therefore, it is necessary acknowledge their presence by different
Rosalba Sevilla-Montoya, Maria de Jesus Zavaleta-Abreu, Gloria Queipo, Silvia Sanchez, Sara Frias, Alberto Hidalgo-Bravo, Patricia Grether-González   +6 more
doaj   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Cytogenomic description of a Mexican cohort with differences in sex development

Molecular Cytogenetics
Background Differences in Sex Development (DSD) is a heterogeneous group of congenital alterations that affect inner and/or outer primary sex characters. Although these conditions do not represent a mortality risk, they can have a severe psycho-emotional
Grecia C. Olivera-Bernal, Marlon De Ita-Ley, Edgar F. Ricárdez-Marcial, Luz María Garduño-Zarazúa, Ángel Ricardo González-Cuevas, Omar A. Sepúlveda-Robles, Juan Carlos Huicochea-Montiel, Alan Cárdenas-Conejo, Laura Santana-Díaz, Haydeé Rosas-Vargas   +9 more
doaj   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Predicting Gonadal Germ Cell Cancer in People with Disorders of Sex Development; Insights from Developmental Biology

International Journal of Molecular Sciences, 2019
The risk of gonadal germ cell cancer (GGCC) is increased in selective subgroups, amongst others, defined patients with disorders of sex development (DSD).
L. Looijenga, Chia‐Sui Kao, Muhammad T. Idrees   +2 more
semanticscholar   +1 more source