Results 31 to 40 of about 168,585,466 (202)

Clinical evaluation study of the German network of disorders of sex development (DSD)/intersexuality: study design, description of the study population, and data quality

BMC Public Health, 2009
Background The German Network of Disorders of Sex Development (DSD)/Intersexuality carried out a large scale clinical evaluation study on quality of life, gender identity, treatment satisfaction, coping, and problems associated with diagnoses and ...
Jürgensen Martina, Kleinemeier Eva, Kropf Siegfried, Lux Anke, Thyen Ute   +4 more
doaj   +1 more source

Disorders of sex development: mothers’ experiences of support [PDF]

, 2017
Background: An increasing body of research has sought to determine the impact of Disorders of Sex Development (DSD) on the family of the affected child. Little is currently understood about the support needs of the family and how well these needs are met.
Chivers, C., Deiros, M., Burns, J.
core   +1 more source

408 Cases of Genital Ambiguity Followed by Single Multidisciplinary Team during 23 Years: Etiologic Diagnosis and Sex of Rearing

International Journal of Endocrinology, 2016
Objective. To evaluate diagnosis, age of referral, karyotype, and sex of rearing of cases with disorders of sex development (DSD) with ambiguous genitalia. Methods. Retrospective study during 23 years at outpatient clinic of a referral center.
Georgette Beatriz De Paula, Beatriz Amstalden Barros, Stela Carpini, Bruna Jordan Tincani, Tais Nitsch Mazzola, Mara Sanches Guaragna, Cristiane Santos da Cruz Piveta, Laurione Candido de Oliveira, Juliana Gabriel Ribeiro Andrade, Guilherme Guaragna-Filho, Pedro Perez Barbieri, Nathalia Montibeler Ferreira, Marcio Lopes Miranda, Ezequiel Moreira Gonçalves, Andre Moreno Morcillo, Nilma Lucia Viguetti-Campos, Sofia Helena Valente Lemos-Marini, Roberto Benedito de Paiva Silva, Antonia Paula Marques-de-Faria, Maricilda Palandi De Mello, Andrea Trevas Maciel-Guerra, Gil Guerra-Junior   +21 more
doaj   +1 more source

Unravelling complex mosaicism of sex chromosomes in a patient with primary amenorrhea through cytogenetic analysis on urothelial cells

Taiwanese Journal of Obstetrics & Gynecology, 2021
Objective: Sex chromosome mosaicism remains challenging in the study of disorders of sex development (DSD). Aneuploid cells in the developing gonad play a major role in sex determination. Therefore, it is necessary acknowledge their presence by different
Rosalba Sevilla-Montoya, Maria de Jesus Zavaleta-Abreu, Gloria Queipo, Silvia Sanchez, Sara Frias, Alberto Hidalgo-Bravo, Patricia Grether-González   +6 more
doaj   +1 more source

Disorders or Differences of Sex Development? Views of Affected Individuals on DSD Terminology

, 2020
Over a decade ago, the participants at the International Consensus Conference on Intersex proposed Disorders of Sex Development (DSD) as an umbrella term for “congenital conditions in which the development of chromosomal, gonadal, or anatomical sex is ...
Gehrmann, Katharina, Koehler, B, Köhler, Birgit, Lee, Peter, Bouvattier, C, Bennecke, E, Nordenstroem, A, Bouvattier, Clair, Cohen-Kettenis, P, Bennecke, Elena, Röhle, Robert, Gehrmann, K, Thyen, U, Nordenström, Anna, Cohen-Kettenis, Peggy, Thyen, Ute, Roehle, R, Lee, P, Wiesemann, C, Wiesemann, Claudia   +19 more
core   +1 more source

Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9

Nature Communications, 2018
SRY and its target SOX9 are known key determinants in testis development. Here the authors by studying duplications and deletions upstream of SOX9 from patient samples with disorders of sex development (DSD) reveal enhancers for SOX9 critical for human ...
Brittany Croft, Thomas Ohnesorg, Jacqueline Hewitt, Josephine Bowles, Alexander Quinn, Jacqueline Tan, Vincent Corbin, Emanuele Pelosi, Jocelyn van den Bergen, Rajini Sreenivasan, Ingrid Knarston, Gorjana Robevska, Dung Chi Vu, John Hutson, Vincent Harley, Katie Ayers, Peter Koopman, Andrew Sinclair   +17 more
doaj   +1 more source

Genetic Analysis For The Diagnosis of Disorders of Sexual Development in Indonesia

Journal of Biomedicine and Translational Research, 2016
Disorders of sex development (DSD) is defined by congenital conditions in which development of chromosomal, gonadal, or anatomical sex is atypical, while in clinical practice this term means any abnormality of the external genitalia.
Sultana MH Faradz
doaj   +1 more source

Dealing With Uncertainty and Lack of Knowledge in Diverse Sex Development: Controversies on Early Surgery and Questions of Consent

Sexual Medicine, 2020
Introduction: Diverse sex development (dsd) is an umbrella term for different congenital conditions with incongruence of chromosomal, gonadal, and phenotypic sex characteristics.
Ute Lampalzer, PhD, Peer Briken, MD, Katinka Schweizer, PhD   +2 more
doaj   +1 more source

Participation of adults with disorders/differences of sex development (DSD) in the clinical study dsd-LIFE: design, methodology, recruitment, data quality and study population [PDF]

, 2017
Background: dsd-LIFE is a comprehensive cross-sectional clinical outcome study of individuals with disorders/differences of sex development (DSD).
Gehrmann, Katharina, Pienkowski, C, Roehle, Robert, Claahsen-van der Grinten, H.L., Katharina Gehrmann, Cohen-Kettenis, P, Anna Nordenström, Peggy Cohen-Kettenis, Röhle, Robert, Grinten, Hedi,, Pienkowski, Catherine, Catherine Pienkowski, Bouvattier, Claire, Birgit Köhler, Szarras-Czapnik, Maria, Nordenström, Anna, Grinten, Hedi, Claahsen-van Der, Nordenstrom, A, Thyen, Ute, Hedi Claahsen-van der Grinten, Claahsen-van der Grinten, Hedi, Koehler, B, Szarras-Czapnik, M, Köhler, Birgit, Bouvattier, C, on behalf of the dsd-LIFE group, Robert Röhle, Kohler, B., Maria Szarras-Czapnik, Claahsen-van, der Grinten H, Gehrmann, K, null null, Thyen, U, Ute Thyen, Cohen-Kettenis, Peggy, Claire Bouvattier, Roehle, R   +36 more
core   +2 more sources

Transverse testicular ectopia with disorders of sex development

Indian Journal of Urology, 2012
Transverse testicular ectopia (TTE) is a rare congenital anomaly. Although TTE often coexists with abnormalities such as inguinal hernia and persistent Mullerian duct syndrome, disorders of sex development (DSD) in combination with TTE is extremely rare.
Katsuya Aoki, Masaomi Kuwada, Kiyohide Fujimoto, Yoshihiko Hirao   +3 more
doaj   +1 more source