Results 61 to 70 of about 1,348,902 (327)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Regional disparities and convergences in the European Union

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012
This paper analyses the disparities and convergences between 97 regions of the European Union in the period 2000 to 2008. The methodology is based on the Gini coefficient, Disparity Range Coefficient, Average Disparity Range Coefficient, and σ- and β ...
Petr Blížkovský
doaj   +1 more source

Cascade Residual Learning: A Two-stage Convolutional Neural Network for Stereo Matching

open access: yes, 2018
Leveraging on the recent developments in convolutional neural networks (CNNs), matching dense correspondence from a stereo pair has been cast as a learning problem, with performance exceeding traditional approaches.
Pang, Jiahao   +4 more
core   +1 more source

Racial Disparity and Triple-Negative Breast Cancer in African-American Women: A Multifaceted Affair between Obesity, Biology, and Socioeconomic Determinants

open access: yesCancers, 2018
Triple negative breast cancer (TNBC) is a molecularly heterogeneous disease whose incidence is disproportionately higher in African American (AA) women compared to European American (EA) women.
S. Siddharth, D. Sharma
semanticscholar   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

American Medicine and the Politics of Race [PDF]

open access: yes, 2005
Straw men play a major role in the debate over racial disparity in American medicine. Most have been deployed by the disparities-denying right, but progressives intent on “outing” racism have sent forth their share.
Bloche, Maxwell Gregg
core   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

open access: yesMolecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat   +18 more
wiley   +1 more source

The possibilities of complex assessment of the development and categorization of rural areas

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2010
Regions in the Czech Republic, the same as in most European countries, show in their rural areas a considerable difference rate from points of view demographic, social and economic as well as from point of view of infrastructure.
Tomáš Hlavsa
doaj   +1 more source

Changes in characteristics of inpatient respiratory conditions from 2019 to 2021 (before and during the COVID-19 pandemic)

open access: yesFrontiers in Public Health, 2023
BackgroundThe COVID-19 pandemic has resulted in an increase in the number of individuals with respiratory conditions that require hospitalization, posing new challenges for the healthcare system.
Zahra Mojtahedi   +5 more
doaj   +1 more source

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