Results 101 to 110 of about 93,533 (290)

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

Understanding the Implications of Marriage Law Amendments: Marriage Dispensation Cases in Indonesian Religious Courts

Al-Istinbath: Jurnal Hukum Islam
This article aims to determine the implications of changing Law Number 1 of 1974 to Law Number 16 of 2019 concerning Marriage Dispensations in Indonesian Religious Courts.
Yasin Yetta, Ahmad Rajafi, Syahrul Mubarak Subeitan   +2 more
doaj   +1 more source

Business as Usual: The response of the corporate sector to the May 2008 xenophobic violence [PDF]

, 2008
This work set out to fulfil two principal objectives: to investigate the contribution of the corporate sector with particular reference to the mining sector with its reliance on foreign labour, and thereafter to reflect on civil society's response to the
Annsilla Nyar
core  

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Contribution of the P3AP2KB Service in Handling the Impact of Child Marriage in Sleman Regency

Yinyang: Jurnal Studi Islam, Gender dan Anak
The Religious Court is the final solution so that the marriage of a child can occur through the mechanism of requesting a marriage dispensation. The impact of child marriage that often occurs but is rarely realized is baby blues.
Fakih Abdul Rozak, Putri Ayu Nurmalinda, Syarif Hidayatullah   +2 more
doaj   +1 more source

Civilised men -- members of the craft : Freemasonry in Auckland to the formation of the Grand Lodge of New Zealandin 1890 : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in History at Massey University [PDF]

, 2005
The public's fascination with freemasonry seems endless. Freemasons are variously believed to be members of a mysterious brotherhood of enormous influence, a secret society believed to have its roots in the order of the Knights Templar or the Egyptian ...
Gardiner, Carol Elizabeth
core  

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

Advanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman, Hadas Oved, Itay Gil, Amgad Marzook, Ester Sapir Baruch, Yahel Shechter, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

Market Analysis of Plant-based Drugs C. The Cannabis Market [PDF]

, 2017
An estimated quarter of a billion people, or around 5 per cent of the global adult population, used drugs at least once in 2015. Even more worrisome is the fact that about 29.5 million of those drug users, or 0.6 per cent of the global adult population ...

core  

Three‐Dimensional Ovary Model to Improve and Study Murine Follicle Growth

Advanced Healthcare Materials, EarlyView.
To develop new methods for fertility preservation in women, novel culture systems for small follicles need to be established. In this work, a poly(ethylene glycol) based scaffold, with appropriate mechanical and bioactive features to support mouse follicle and ovary cell growth is developed, and the formed cell‐follicle interactions are visualized ...
Mira Jacobs, Valon Gllareva, Lukas Moser, Silvia Pravato, Eric Mora Pimentel, Brigitte Leeners, Martin Ehrbar   +6 more
wiley   +1 more source