Results 31 to 40 of about 120,243 (219)
Ecosphere, 2021 Whether cities are more or less diverse than surrounding environments, and the extent to which non‐native species in cities impact regional species pools, remain two fundamental yet unanswered questions in urban ecology.
Christopher M. Swan +10 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Genetics and Molecular Biology, 2002 Hydromedusa maximiliani is a vulnerable neotropical freshwater turtle endemic to mountainous regions of the Atlantic rainforest in southeastern Brazil.
Franco L. Souza +4 more
doaj +1 more source
Ecology and Evolution, 2021 The natural and seminatural components of agricultural landscapes play a key role in maintaining a high level of biodiversity. Being the Po Valley one of the most human‐dominated and intensively cultivated landscapes in Europe, we investigated the effect
Francesca Della Rocca +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Conservation Letters, 2022 Fire can promote biodiversity, but changing patterns of fire threaten species worldwide. While scientific literature often describes ‘‘inappropriate fire regimes’’ as a significant threat to biodiversity, less attention has been paid to the ...
Julianna L. Santos +6 more
doaj +1 more source
A new dispersal area of roe deer(Capreolus capreolus L. 1758): Karagüney Mountains, Kırıkkale
Turkish Journal of Forestry, 2021 Roe deer (Capreolus capreolus L. 1758) is spread all over Europe, including in the west of Russia, and in the Anatolian and Caucasian regions. Roe deer is found in the Marmara, Black Sea regions, Hakkari, Izmir, and Amanos Region.
Ali Uğur Özcan
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source