Results 31 to 40 of about 489,611 (243)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Finura y su dispersión. [PDF]

open access: yes, 1973
Exposición sobre la importancia de la finura, su dispersión y la influencia sobre la regularidad del hilo.Peer ...
Pons Casacuberta, José María
core   +1 more source

Immigration and demographic change in the metropolitan area of Madrid

open access: yesAnales de Geografía de la Universidad Complutense, 2009
The paper analyzes the evolution of the population and its dynamic components in the metropolitan area of Madrid between 1996 and 2006. Work has been done with data from the Municipal Population Census and the Movement of Natural Population.
Enrique Pozo Rivera   +1 more
doaj  

DENSIDAD FONONICA Y POTENCIAL DE DEFORMACION

open access: yesRevista de Investigación de Física, 2006
En las últimas décadas se ha desarrollado métodos computacionales para la simulación de modelos de sistemas líquidos y amorfos utilizando potenciales de pares para la formulación de la energía total de una determinada sustancia con métodos del espacio ...
Luis Salazar de Paz
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Applet de dispersión de la luz

open access: yes, 2021
Podeu consultar la versió en castellà a: http://hdl.handle.net/2445/14392 ; i en anglès a: http://hdl.handle.net/2445/14563En esta aplicación se muestran los fenómenos de dispersión cromática de la luz.
Carnicer González, Arturo   +9 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Dispersión de insectos [PDF]

open access: yes, 2013
En el siguiente trabajo se deduce un modelo para estudiar la dinámica espacio-temporal de una población considerándola como un proceso de difusión, el enfoque a considerar es una consecuencia del modelo de camino aleatorio, luego se resuelve el modelo ...
Estrada Kassir, Eduardo
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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