Results 51 to 60 of about 489,611 (243)

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

The urban form effect of population and housing dispersion concentration in Culiacan Rosales / La forma urbana efecto de la concentración dispersión de la población en Culiacán Rosales

open access: yesContexto: Revista de la Facultad de Arquitectura Universidad Autónoma de Nuevo León, 2019
This work is a research in progress. The urban dispersion or concentration is studied through population and housing density indicators constructed in the context of Culiacán Rosales, in an attempt to explain the urban form that is understood as the
Jorge Javier Acosta Rendón
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Aplicación de un modelo de dispersión de gases contaminantes en el proceso de fabricación de ladrillos artesanales en la ciudad de Ibarra y su relación con la salud humana

open access: yes, 2019
En el barrio el Tejar y las parroquias La Esperanza y Caranqui se encuentra como actividad artesanal la fabricación de ladrillos artesanales que se ha desarrollado a lo largo de mucho tiempo y se ha transmitido de generación en generación.
Tobar Hidalgo, Isaac Darío
core  

Estudio numérico y experimental de los flujos atmosféricos y dispersión de contaminantes en entornos urbanos = Numerical and experimental study of atmospheric flows and pollutant dispersion in urban environment

open access: yes, 2006
La contaminación atmosférica en entornos urbanos se ha convertido en los últimos años en uno de los problemas medio ambientales más importantes. Por este motivo, tanto las autoridades como la comunidad científica han prestado una atención especial al ...
Santiago del Río, José Luis
core   +1 more source

Walter Benjamin: dispersión y educación en la época contemporánea

open access: yesCo-herencia: Revista de Humanidades, 2015
Me propongo plantear en este artículo algunas consideraciones relativas al concepto de dispersión, que apunten a la comprensión de una dinámica determinante de la vida contemporánea.
Germán Darío Velez López
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

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