Results 171 to 180 of about 418,870 (216)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Myocardial Work Index Dispersion as a Potential Predictor of Ventricular Arrhythmias in Patients with Heart Failure with Reduced Ejection Fraction. [PDF]

Biomedicines
Dąbrowska M, Potapowicz-Krysztofiak M, Życzkowska P, Maciorowska M, Orski Z, Winkler A, Krzesiński P, Kiliszek M, Uziębło-Życzkowska B.   +8 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Validation of Pure and Total Movement Dispersion Variables as Measures of the Distribution of Daily Activity Using Accelerometers: A Secondary Analysis of a Prospective Cohort. [PDF]

J Public Health (Berl)
Klamm MM, Yan Y, Duck A, Sung JH, Gabriel KP, Schrack JA, Stosor V, Detels R, Patel SR, Fischl MA, Gange SJ, Konkle-Parker D.   +11 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Direct observations of submesoscale turbulence driving mesoscale eddy leakage. [PDF]

Sci Adv
Cao H, Jing Z, Fox-Kemper B, Qiu B, Lacasce JH, Yan T.   +5 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Comparing Symmetry-Adapted Perturbation Theory to Intermolecular Energy Decomposition Analysis Based on Absolutely Localized Molecular Orbitals. [PDF]

J Chem Theory Comput
Puthillathu N, Gray M, Herbert JM.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Genetic Dynamics and Dispersion Pattern Changes in <i>Aedes aegypti</i> Populations (Diptera: Culicidae) in Yunnan Province, China, over Three Consecutive Years. [PDF]

Insects
Gao J, Zhang HD, Wu ZM, Shi QM, Xing D, Guo XX, Li CX, Dong YD, Zhao TY, Chu HL.   +9 more
europepmc   +1 more source