Results 261 to 270 of about 2,679,470 (331)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A Theoretical Investigation on the Hydrogen Bond Based on the GLED Method of Bonding Analysis. [PDF]

J Comput Chem
Borocci S, Grandinetti F, Sanna N, Zazza C.   +3 more
europepmc   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Physicochemical Characteristics of Potato Starch Extrudates Enriched with Edible Oils. [PDF]

Molecules
Włodarczyk-Stasiak M, Jurak M, Wiącek AE.   +2 more
europepmc   +1 more source

Discovery of an Ideal Quadratic Nodal Point in Two-Dimensional Binary Compound C₅P₁. [PDF]

ACS Omega
Li Y.
europepmc   +1 more source

The emergence of trust under conditions of distrust. [PDF]

Sci Rep
Fehlhaber AL.
europepmc   +1 more source

Effect of Ionomer-Solvent Interactions in PFSA Dispersions: Dispersion Viscosity. [PDF]

Macromolecules
Novy M, Duchesne D, Dahlke G, Chen LP, Moore RB.   +4 more
europepmc   +1 more source

Revealing the Character of Coordination Bonding in 2D Metal-Organic Frameworks. [PDF]

Adv Sci (Weinh)
Brandstetter D, Mearini S, Windischbacher A, Grisan Qiu YY, Baranowski D, Feyer V, Schneider CM, Puschnig P.   +7 more
europepmc   +1 more source

Computational analysis of X₂CaZnH₆ (X = K, Rb and Cs) hydrides for hydrogen storage. [PDF]

Sci Rep
Al-Zoubi N, Almahmoud A, Almahmoud A, Jaradat A, Obeidat A.   +4 more
europepmc   +1 more source