Results 91 to 100 of about 1,346,635 (301)

Application of Microtremor Exploration in Loess Strata Division

open access: yesTaiyuan Ligong Daxue xuebao
[Purposes] During the deposition process, loess is significantly influenced by climatic conditions, exhibiting distinct layering alternations between loess and paleosols.
ZHANG Jihong   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Dispersion-managed soliton fiber laser with random dispersion, multiphoton absorption and gain dispersion

open access: yes, 2018
We address the generation and interaction of dispersion-managed dissipative solitons (DMDS) in a model of fiber lasers with the cubic-quintic nonlinearity, multiphoton absorption and gain dispersion.
B. A. Malomed (14357538)   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Fibre Bragg gratings for dispersion compensation in optical communications

open access: yes, 1997
The main activities and recent developments towards the implementation of meter-long, high-performance fibre grating dispersion compensators in the Optoelectronics Research Centre, Southampton University are reviewed.
Laming, R.I.   +5 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Estimating Fundamental Cross-Section Dispersion from Fixed Event Forecasts [PDF]

open access: yes
A couple of recent papers have shifted the focus towards disagreement of professional forecasters. When dealing with survey data that is sampled at a frequency higher than annual and that includes only fixed event forecasts, e.g.
Jonas Dovern, Ulrich Fritsche
core   +2 more sources

Spatial Heterogeneity and the Wage Curve Revisited [PDF]

open access: yes
Most ‘wage curve’ studies treat local labour markets as independent ‘islands’ in the national economy. However, when a local labour market is in close proximity of other labour markets, a local shock that increases unemployment may not lead to lower pay ...
Simonetta Longhi   +2 more
core  

Understanding the trap-induced frequency dispersion in the C–V curve of AlGaN/GaN hetero-structure

open access: yes
This article investigates the trapping mechanism in AlGaN/GaN heterostructure. For our study, the traps within the AlGaN layer are introduced at the interface and near the interface of AlGaN/GaN, in the SILVACO TCAD tool.
Joshi, Vikas   +4 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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