Results 51 to 60 of about 96,778 (297)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Temperature-Sensitive Modified Bentonite Based on NIPAM for Drilling Fluid: Experimental and Molecular Simulation Studies

open access: yesMolecules, 2023
Bentonite is an important component of drilling fluid, whose quality directly affects the safety and economic benefits of water-based drilling fluid. In order to effectively cope with temperature changes, the development of temperature-sensitive modified
Yi Pan   +8 more
doaj   +1 more source

PECULIARITIES OF REFRACTIVE INDEX DISPERSION OF TGS CRYSTALS [PDF]

open access: yesCondensed Matter Physics, 1999
???? ???????????? ??????????????????????????? ?????????????????????????? ???????????????? ????????????????-??????????????, ?????? ????????????????? ???????????? ?????????????????? ???????????????????? n(??) ??????????????????????, ???????????????????????????????? ?????????????????? ?? ?????????????? ???????????????????? (??), ?? ???????? ???????????????
Myshchyshyn, O.Ya.   +3 more
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Fiber-specific structural properties relate to reading skills in children and adolescents

open access: yeseLife, 2022
Recent studies suggest that the cross-sectional relationship between reading skills and white matter microstructure, as indexed by fractional anisotropy, is not as robust as previously thought.
Steven Lee Meisler, John DE Gabrieli
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

The Role of Ultrasound Shear Wave Dispersion Imaging in Evaluating Carotid Viscoelasticity:A Preliminary Study [PDF]

open access: yesAdvanced Ultrasound in Diagnosis and Therapy, 2019
Objective: To evaluate the carotid viscoelasticity using ultrasound shear wave dispersion imaging (USWD) and determine its feasibility.Methods: Fifty-three volunteers were recruited and divided into the group1 (≥50 years old) and group 2 (<50 years ...
Xianghong Luo, MD, Jianhui Zhang, MD, Sihui Shao, MD, Min Yan, MD, Rong Wu, MD, Lianfang Du, MD, Zhaojun Li, MD
doaj   +1 more source

Analysis of self--averaging properties in the transport of particles through random media

open access: yes, 1994
We investigate self-averaging properties in the transport of particles through random media. We show rigorously that in the subdiffusive anomalous regime transport coefficients are not self--averaging quantities.
B. Derrida   +15 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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