Results 51 to 60 of about 15,548 (262)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Underground SpaceDiscontinuity is critical for strength, deformability, and permeability of rock mass. Set information is one of the essential discontinuity characteristics and is usually accessed by orientation grouping.
Keshen Zhang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Nanomaterials, 2020 Understanding and modeling of a surface-plasmon phenomenon on lossy metals interfaces based on simplified models of dielectric function lead to problems when confronted with reality.
Krystyna Kolwas, Anastasiya Derkachova
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
工程科学与技术, 2022 The comprehensive assessment of severity degree of dam failure impact is an important part of dam risk evaluation and management. There are two major problems identified in the traditional comprehensive evaluation of dam break consequences: Constant ...
Zongkun LI +3 more
doaj
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Probing the Relationship between Urban Primacy and Economic Development: A Cross-country Analysis [PDF]
نشریه جغرافیا و برنامهریزی, 2014 According to a prevalent belief since the 1960s, patterns of national spatial systems have been thought to be dynamically transmuted appropriate to the levels of national economic growth and development until a rather balanced and efficient hierarchy of ...
Ahmad Sharbatoghlie, Heydar Javanmard
doaj
Price index dispersion and utilitarian social evaluation [PDF]
Economics Letters, 2005 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources