Results 61 to 70 of about 29,481 (310)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Advanced fibre Bragg gratings: application to dispersion compensation [PDF]
This thesis presents the design and fabrication issues related to advanced fibre Bragg gratings with particular emphasis on realising novel devices with application to dispersion compensation.
Durkin, Michael Kevan
core
Cascaded chiral birefringent media enabled planar lens with programable chromatic aberration
Wavefront control is the fundamental requirement in optical informatics. Planar optics have drawn intensive attention due to the merits of compactness and light weight.
Dewei Zhang +7 more
doaj +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
A Tunable Dispersion Waveguide Based on Graphene–Silicon Lateral Slot Geometric Structure
The dispersion profiles of a hybrid graphene–silicon (HyGS) slot waveguide with trilayers of graphene are investigated in this paper. By tuning the bias voltage on graphene layer, the zero dispersion wavelengths (ZDW) of HyGS slot waveguide can be
Zhen Li +4 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Efficient near-infrared supercontinuum generation in tellurite holey fiber pumped 320nm within the normal dispersion regime [PDF]
We demonstrate the generation of a 1.1-1.7µm supercontinuum in a 1.3m long air suspended-core tellurite holey-fiber with a nominal zero-dispersion wavelength of ~1.38µm. The fiber is pumped at 1.06µm with a 20ps pulsed fiber laser.
Horak, P. +19 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source

