Results 81 to 90 of about 88,487 (267)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Beta-Effect of Internal Inertia–Gravity Waves in a Stratified Atmosphere in the Incompressible Fluid Approximation

open access: yesAtmosphere
This paper presents a mathematical model that describes the propagation of internal inertia–gravity waves in a stratified atmosphere under the approximations of an incompressible fluid and a traditional β-plane.
Robert G. Zakinyan   +2 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Dispersion Relations and Inconsistency of ρ Data [PDF]

open access: yes, 2003
The high energy elastic nucleon cross section is treated from the viewpoint of the basic principles of local field theory. The connection between the energy dependence of $σ_{tot}$ and the $ρ$ - ratio of the real to imaginary parts of the forward elastic scattering amplitude is examined in the framework of dispersion relations, derivative dispersion ...
openaire   +2 more sources

Phonon Transport Characteristics of Nano-Silicon Thin Films Irradiated by Ultrafast Laser under Dispersion Relation

open access: yesBuildings
The gray model simplifies calculations by ignoring phonon polarization, but sacrifices a certain level of computational accuracy. In effect, the frequency and wavevector of phonons form complex polarization patterns, which means their propagation modes ...
Yudong Mao   +6 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

To the dependence of speed spray distribution of gravitational waves in the atmosphere of latitude

open access: yesНаука. Инновации. Технологии, 2022
Introduction: Waves in the atmosphere play an important role, as they determine both the intensity of weather-forming phenomena and the speed of their movement. The truth remains the question of the reason for the excitation of planetary waves.
E. G. Nabrodova   +3 more
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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