Results 41 to 50 of about 638,439 (343)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

A vision for restitution in Myanmar

open access: yesForced Migration Review, 2018
People displaced in Myanmar during decades of civil conflict, as well as more recently displaced persons, need accessible legal pathways and assistance to regain access to their land and properties.
José Arraiza, Scott Leckie
doaj  

Displacements

open access: yes, 2019
In this work we establish a theory of Calculus based on the new concept of displacement. We develop all the concepts and results necessary to go from the definition to differential equations, starting with topology and measure and moving on to differentiation and integration.
Albés, Ignacio Márquez   +1 more
openaire   +2 more sources

Displacing displacement: narratives for a haunting history [PDF]

open access: yesJournal of Modern Italian Studies, 2022
In this article, building on recent theories of displacement, I propose a definition of post-displacement as a ‘displacement of displacement’, or the displacement of already displaced histories. The analysis focuses on the ethnographic case of Latina, an Italian city built in 1932 by the Fascist regime.
openaire   +2 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Criminal violence and displacement in Mexico

open access: yesForced Migration Review, 2014
Rampant criminal violence, from direct coercion and physical threats to the erosion of the quality of life and livelihood opportunities, pushes people to move in a variety of ways. Not everyone forced to move has equal access to protection or asylum.
Sebastián Albuja
doaj  

When wounds travel

open access: yesMedicine Anthropology Theory, 2015
This article explores trauma as a form of ‘social wound’, entrenched in the intersections of local histories and social experiences of violence and displacement. Building on ethnographic accounts of displacement of Iraqis in Lebanon in the wake of the US
Omar Dewachi
doaj   +1 more source

Analysis and calibration of star sensor's image plane displacement [PDF]

open access: yesInfrared and Laser Engineering, Vol.43 No.10, 2014, 2018
Star sensor's image plane can have three kinds of displacement after a long time working in space, and the displacements are the principal point drift, incline displacement and rotation displacement. These displacements can severely decrease star sensor's measuring accuracy, therefore it's necessary to analyze and calibrate them.
arxiv  

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

The importance of monitoring internal displacement

open access: yesForced Migration Review, 2018
The 2030 Agenda for Sustainable Development acknowledges the link between internal displacement and development, and States should therefore be including internal displacement when monitoring progress towards their development goals.
Christelle Cazabat
doaj  

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