Results 41 to 50 of about 2,164,098 (281)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The same distant places: Bob Dylan's poetics of place and displacement [PDF]

open access: yes, 2009
This article explores the emphasis in Bob Dylan's work on memory, place, and displacement. It rehearses some key issues raised by recent theorists who have been interested in the connections between these themes before proceeding to discuss tropes of ...
Elliott, Richard
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Modelling displacement

open access: yesForced Migration Review, 2015
Although those seeking a single global prediction will be disappointed, today’s models of climate change- and disaster-induced displacement can provide a range of scenarios for specific countries, regions or hotspots.
Justin Ginnetti
doaj  

Migration corridors in Africa and access to health services: Current challenges and a path forward for research and practice

open access: yesJournal of Public Health in Africa
This commentary discusses migration corridors on the African continent and access to health services. It stems from a workshop on migration corridors held in South Africa and reflects the interdisciplinary collaborative dialogue on migration journeys and
Edward Kirumira   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Climate change interventions at the “top of the world”: exploring risk–risk tradeoffs in Arctic coastal protection and forest carbon removal in Alaska

open access: yesFrontiers in Political Science
Alaska, the largest geographic state in the United States, experiences climate change and global warming two to three times that of the global average, leading to thawing permafrost, wildfires, and more severe storms.
Benjamin Sovacool
doaj   +1 more source

Polyimidazoles via aromatic nucleophilic displacement [PDF]

open access: yes, 1991
Polyimidazoles (PI) are prepared by the aromatic nucleophilic displacement reaction of di(hydroxyphenyl) imidazole monomers with activated aromatic dihalides or activated aromatic dinitro compounds. The reactions are carried out in polar aprotic solvents
Connell, John W., Hergenrother, Paul M.
core   +2 more sources

Mirror displacement energies and neutron skins [PDF]

open access: yes, 2002
A gross estimate of the neutron skin [0.80(5)$(N-Z)/A$ fm] is extracted from experimental proton radii, represented by a four parameter fit, and observed mirror displacement energies (CDE).
A. Krasznahorkay   +23 more
core   +4 more sources

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

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