Results 41 to 50 of about 2,289,456 (329)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Seismic displacement transducer Patent [PDF]

open access: yes, 1965
Determining sway of buildings by low frequency device using ...
Greenwood, T. L.
core   +1 more source

Displacement- and Timing-Noise Free Gravitational-Wave Detection

open access: yes, 2006
Motivated by a recently-invented scheme of displacement-noise-free gravitational-wave detection, we demonstrate the existence of gravitational-wave detection schemes insusceptible to both displacement and timing (laser) noises, and are thus realizable by
A. Abramovici   +5 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Climate change interventions at the “top of the world”: exploring risk–risk tradeoffs in Arctic coastal protection and forest carbon removal in Alaska

open access: yesFrontiers in Political Science
Alaska, the largest geographic state in the United States, experiences climate change and global warming two to three times that of the global average, leading to thawing permafrost, wildfires, and more severe storms.
Benjamin Sovacool
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Modelling displacement

open access: yesForced Migration Review, 2015
Although those seeking a single global prediction will be disappointed, today’s models of climate change- and disaster-induced displacement can provide a range of scenarios for specific countries, regions or hotspots.
Justin Ginnetti
doaj  

Resisting Displacement in the Southwest Bronx: Lessons from CASA's Tenant Organizing [PDF]

open access: yes, 2017
CASA is proud to present our new white paper, Resisting Displacement: Lessons from CASA's Tenant Organizing in the Southwest Bronx!In the last year, CASA has organized or provided technical assistance to over 90 buildings, which are home to more than 7 ...
Adrien Weibgen   +6 more
core  

From random walk to single-file diffusion

open access: yes, 2005
We report an experimental study of diffusion in a quasi-one-dimensional (q1D) colloid suspension which behaves like a Tonks gas. The mean squared displacement as a function of time is described well with an ansatz encompassing a time regime that is both ...
Bianxiao Cui   +7 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

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