Results 111 to 120 of about 1,132,423 (301)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Studying the Freezing Law of Reinforcement by Using the Artificial Ground Freezing Method in Shallow Buried Tunnels

Applied Sciences
In this paper, the freezing and strengthening project of the Sanya estuary tunnel is analyzed, which is facilitated by the use of the partial differential equation (PDE) module in COMSOL Multiphysics software.
Peng Liu, Jun Hu, Qinxi Dong, Yongzhan Chen   +3 more
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Submicron Deformation Field Measurements II: Improved Digital Image Correlation [PDF]

, 1994
This is the second paper in a series of three devoted to the applicaiton of Scanning Tunneling Microscopy to mechanics problems. In this paper improvements to the Digital Image Correlation method are outlined, a technique that compares digital images of ...
Knauss, W. G., Vendroux, G.
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

A theoretical model of displacement response of clamped circular plate under multiple far-field blast loads

Baozha yu Chongji
Regarding the displacement response of clamped circular plates under multiple far-field blast loads, we proposes a novel theoretical modeling approach based on membrane theory energy equations, by simplifying multiple blast loads into linearly decaying ...
Xiaobo ZHENG, Hongtao ZHAO, Teng LI, Weiguang YAO, Haisheng SONG, Yulin GUI, Zhi WANG   +6 more
doaj   +1 more source

Thermoelectroelastic response of a piezoelectric cylinder with D∞ symmetry under axisymmetric mechanical and thermal loading

Mechanical Engineering Journal, 2017
Carbon-neutral and biodegradable materials such as wood and poly-L-lactic acid play an important role in reducing environmental loads. Therefore, this study theoretically analyzed the thermoelectroelastic problem for a solid cylinder with D∞ symmetry ...
Masayuki ISHIHARA, Yoshihiro OOTAO, Yoshitaka KAMEO, Takuro SAITO   +3 more
doaj   +1 more source

Embedded discontinuities for softening solids [PDF]

, 1999
Additional, discontinuous functions are added to the displacement field of standard finite elements in order to capture highly localised zones of intense straining.
Sluys, LJ, Wells, GN
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Some Consequences of the Law of Local Energy Conservation in Electromagnetic field [PDF]

, 2001
At electromagnetic interactions of particles there arises defect of masses, i.e. the energy is liberated since the particles of the different charges are attracted.
Beshtoev, Kh. M.
core   +2 more sources