Results 91 to 100 of about 1,132,423 (301)

Inversion of the Diffraction Pattern from an Inhomogeneously Strained Crystal using an Iterative Algorithm

open access: yes, 2007
The displacement field in highly non uniformly strained crystals is obtained by addition of constraints to an iterative phase retrieval algorithm. These constraints include direct space density uniformity and also constraints to the sign and derivatives ...
A. A. Minkevich   +9 more
core   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Global Ultrasound Elastography Using Convolutional Neural Network

open access: yes, 2018
Displacement estimation is very important in ultrasound elastography and failing to estimate displacement correctly results in failure in generating strain images.
A Pesavento   +11 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Coulomb stress effects of the April 3, 2024 Hualien, Taiwan, China MS 7.3 earthquake on the surrounding faults and subsequent April 23, 2024 MS 6.2 and MS 6.3 earthquakes

open access: yesDizhi lixue xuebao
Objective  To determine the rupture mode of the MS 7.3 earthquake in Hualien, Taiwan, China on April 3, 2024 and its triggering effect on subsequent seismic events in the surrounding area, the co-seismic displacement field and the induced areal strain ...
GU Peiyuan   +4 more
doaj   +1 more source

Damage Detection in a Polymer Matrix Composite from 4D Displacement Field Measurements. [PDF]

open access: yesMaterials (Basel), 2023
Mandić A   +5 more
europepmc   +1 more source

Initial conditions for cold dark matter particles and General Relativity

open access: yes, 2013
We describe the irrotational dust component of the universe in terms of a relativistic gradient expansion and transform the resulting synchronous metric to a Newtonian coordinate system.
Rampf, Cornelius, Rigopoulos, Gerasimos
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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