Results 91 to 100 of about 72,190 (311)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Reduction of pile head displacement for restrained-head single pile
KSCE Journal of Civil Engineering, 2009 The effect of pile head fixity on the displacement of laterally loaded pile groups was investigated using analytical methods. The reduction of lateral displacement by a pile cap is generalized using a reduction factor, and the effect of soil and pile properties was investigated through a parametric study using the Davies and Budhu method.
Jinoh Won, Fred H. Kulhawy
openaire +1 more source
Response of pile-guided floats subjected to dynamic loading [PDF]
, 2013 Pile-guided floats can be a desirable alternative to stationary berthing structures. Both floats and guide piles are subjected to time varying (dynamic) forces such as wind-generated waves and impacts from vessels.
Quan, Zhili, 权致力
core
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
A Study of Horizontal Displacement of Laterally Loaded Piles
Tikrit Journal of Engineering Sciences, 2013 A theoretical approach is used to analyze single pile and pile in group under lateral loading using two programs. The first one used the finite element method for single pile depending on plain strain condition while the second one used the ...
Aram M. Raheem
doaj
Advances in Civil EngineeringBy relying on the foundation engineering of pile foundations for the Chengdu Metro Line 27 shield tunneling through interchange bridges, three-dimensional numerical simulation results are used to verify field measurements.
Yanpeng Du, Peng Zhang, Jiabing Zhang
doaj +1 more source
Isostaticity in two dimensional pile of rigid disks
, 2003 We study the static structure of piles made of polydisperse disks in the rigid limit with and without friction using molecular dynamic simulations for various elasticities of the disks and pile preparation procedures.
Ball R. C. +5 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Pile-Soil Interaction in Unsaturated Soil Conditions [PDF]
, 2014 The degree of saturation has been proven to significantly affect geotechnical engineering designs for foundations. The changes in water content will influence the way the soil behaves, including its strength and stiffness parameters.
Hamilton, Megan
core +2 more sources