Results 81 to 90 of about 72,190 (311)

Results of monitoring at the British library excavation [PDF]

open access: yes, 2014
The main phase of excavation for the basements of the British Library at St Pancras, London, was completed in 1987. The project included basements extending up to 25 m deep, through the London Clay and into the Lambeth Group. The excavations were formed
Simpson, Brian, Vardanega, Paul J.
core   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The study of pile foundation displacement caused by adjacent excavation of underground super large space

open access: yes矿业科学学报, 2017
It is vital to control the deformation of adjacent structures and displacement of ground caused by the excavation of underground super large space.Based on a span line adjacent to Liao gongzhuang Station which is a super large space excavation ...
Li Tao   +4 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Performance of shallow anchor in ice-rich silt [PDF]

open access: yes, 2014
Thesis (M.S.) University of Alaska Fairbanks, 2014Shallow anchor systems have been widely used for decades due to their time and cost efficiency. Yet when it comes to cold regions like Alaska, new challenges caused by the harsh environment need to be ...
Lin, Chuang, 林闯
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

A contact problem aplication for the local behaviour of soil pile interaction [PDF]

open access: yes, 2017
In geotechnical engineering, the main parameter for the performance of structures such as reinforced walls or deep foundations is often the shaft bearing capacity.
Baeßler, Matthias   +4 more
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Field Test and Numerical Simulation of Squeezing Effect of Large-Diameter Pipe Piles

open access: yesAdvances in Civil Engineering
In order to study the squeezing effect of static press large-diameter single pile and piles group in layered soil, field tests of static press large-diameter pipe piles were carried out based on a project under construction, and numerical simulations of ...
Yongqiang An   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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