Results 141 to 150 of about 242,073 (299)
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Conference: Displacements, in and out of Ethiopia
, 2018 CONFÉRENCE/CONFERENCE 'Displacements' 2018 Biennial Meeting of the Society for Cultural Anthropology / Cosponsored by the Society for Visual Anthropology / CFEE panel+node Displacements, in and out of Ethiopia Date: Friday April 20, 2018, 8:30am-4:30pm ...
Secrétaire Scientifique
core
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Health Harms Associated With Forced Displacements Among People Who Use Drugs in San Francisco, California. [PDF]
Subst Use Addctn JChung EO +6 more
europepmc +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
Forced displacements at the human-animal interface: a narrative review of knowledge gaps and One Health insights. [PDF]
Int HealthCasti G +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
Universal Displacements in Anisotropic Linear Cauchy Elasticity [PDF]
Universal displacements are those displacements that can be maintained for any member of a specific class of linear elastic materials in the absence of body forces, solely by applying boundary tractions. For linear hyperelastic (Green elastic) solids, it
Yavari, Arash, Sfyris, Dimitris
core +1 more source